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Healthy Participants clinical trials

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NCT ID: NCT03174041 Completed - Clinical trials for Healthy Participants

A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin

Start date: April 18, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the potential for a drug interaction between GDC-0853 and midazolam, itraconazole, rosuvastatin, and simvastatin.

NCT ID: NCT03173170 Completed - Clinical trials for Healthy Participants

A Study to Evaluate the Effect of the Potent Cytochrome P-450 3A4 (CYP3A4) Inhibitor Itraconazole on the Pharmacokinetics (PK) of TAK-954 in Healthy Adult Participants

Start date: May 31, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the effect of the potent CYP3A4 inhibitor itraconazole on the single-dose PK of TAK-954.

NCT ID: NCT03161405 Completed - Clinical trials for Healthy Participants

A Study to Evaluate the Effect of the Potent CYP3A4 Inhibitor Itraconazole on the Pharmacokinetics (PK) of TAK-906 in Healthy Participants

Start date: June 5, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the effect of the potent cytochrome P-450 (CYP) 3A4 inhibitor (itraconazole) on the single-dose PK of oral TAK-906 maleate.

NCT ID: NCT03133468 Completed - Clinical trials for Healthy Participants

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AJM347 in Healthy Male Caucasian and Japanese Subjects in the Fasted and Fed State

Start date: July 25, 2017
Phase: Phase 1
Study type: Interventional

This study will be conducted to determine the safety and tolerability of single and multiple oral ascending doses of AJM347 in healthy male participants, and to assess the pharmacodynamic response following single and multiple oral ascending doses of AJM347 in the same population. This study will also aim to determine the single and multiple oral ascending dose pharmacokinetics of AJM347 and its metabolite in healthy male participants, and to determine the effect of food on the single and multiple oral dose pharmacokinetics of AJM347 and its metabolite in the same population.

NCT ID: NCT03106792 Completed - Clinical trials for Healthy Participants

A Clinical Trial to Evaluate the Effectiveness of Hairfinity on Improving Hair Health and Rate of Growth

Start date: July 24, 2017
Phase: Phase 2
Study type: Interventional

The primary outcome of the study is the effect of Hairfinity vs. Placebo on the rate of distal hair growth, assessed using Trichoscan HD, in healthy female adults from baseline to day 90 (end of study).

NCT ID: NCT03085836 Completed - Clinical trials for Healthy Participants

A Pharmacokinetic Study of TAK-438 in Healthy Adult Chinese Participants

Start date: April 19, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the pharmacokinetics (PK) of TAK-438 in healthy adult Chinese participants after both single and multiple dose administration.

NCT ID: NCT03083639 Completed - Clinical trials for Healthy Participants

A Study to Evaluate the Bioequivalence of Single Oral Dose of Esomeprazole Capsule and Tablet Formulation in Healthy Participants

Start date: March 27, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the bioequivalence of esomeprazole 40 milligram (mg) tablets and capsules.

NCT ID: NCT03082235 Completed - Clinical trials for Healthy Participants

Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E6742 in Healthy Adult Subjects

Start date: March 3, 2017
Phase: Phase 1
Study type: Interventional

Study E6742-A001-001 is a randomized, double-blind, placebo-controlled, single ascending dose study conducted to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of single ascending oral doses of E6742 in healthy adult participants.

NCT ID: NCT03055962 Completed - Clinical trials for Healthy Participants

Study to Evaluate the Safety and Tolerability of a Once Daily Dose of 50 mg E2609 in Healthy Japanese Subjects

Start date: February 14, 2017
Phase: Phase 1
Study type: Interventional

Study E2609-J081-014 is a single-center, randomized, double-blind, placebo-controlled study conducted to evaluate the safety and tolerability of multiple oral doses of E2609 50 milligrams (mg), administered once daily for 14 days, in healthy Japanese participants aged 50 to 85 years.

NCT ID: NCT03054194 Completed - Clinical trials for Healthy Participants

Study to Assess the Safety, Tolerability, and Pharmacokinetics of E2730

Start date: January 31, 2017
Phase: Phase 1
Study type: Interventional

Study E2730-A001-001 is a first-in-human, sequential ascending single dose, placebo-controlled study to evaluate the safety, tolerability, and pharmacokinetics (PK) of a single oral dose of E2730 in healthy participants.