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Healthy Older Adults clinical trials

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NCT ID: NCT05874999 Completed - COPD Clinical Trials

Acute Effects of Supramaximal High-Intensity Interval Training in People With COPD

COPD-HIIT-AC
Start date: March 7, 2022
Phase: N/A
Study type: Interventional

High-intensity exercise is essential for optimal development of cardiorespiratory fitness and health. This is, however, challenging for most people with chronic obstructive pulmonary disease (COPD) due to ventilatory limitations, leading to exercise at lower intensities accompanied by suboptimal stress on the cardiovascular and muscular system. The aims of this cross-over trial is: 1. To compare the acute effects of short-duration supramaximal high-intensity interval training (HIIT) vs. traditional moderate-intensity continuous training (MICT) in people with COPD and matched healthy controls (HC). 2. To investigate the feasibility of supramaximal HIIT in people with COPD and matched HC. 3. To compare the cardiorespiratory demand, exercise intensity and symptoms during a modified Borg Cycle Strength Test (BCST) and a cardiopulmonary exercise test (CPET) in people with COPD and HC.

NCT ID: NCT05812651 Completed - Clinical trials for Healthy Older Adults

Effects of Induced Inspiratory Muscle Fatigue on Functional Mobility of Older Adults

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The aim of study was to evaluate the effects of inspiratory induced muscle fatigue on functional mobility of older adults. Though, limited literature exists regarding inspiratory muscle fatigue and its consequences on functional activities of daily living and balance. Yet, it is not clear how improvement in inspiratory muscle strength is related with improvement in functional mobility.

NCT ID: NCT04608370 Completed - Intervention Clinical Trials

Transcranial Photobiomodulation Intervention for Healthy Older Adults

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

Transcranial photobiomodulation (tPBM) is a novel, non-invasive neurostimulation technique, which has shown compelling potential for cognitive improvement. Increasing neuroimaging studies have demonstrated that functional brain network models would sensitively and comprehensively delineate action mechanisms of multiple neurostimulation techniques. However, the action mechanism of tPBM based on functional brain network remain largely unknown. In this project, the investigators aim to investigate the effectiveness of tPBM on working memory for healthy older adults. Taking the randomized, single-blind controlled method, participants in the active tPBM group will take active tPBM, and those in the sham tPBM group will take sham tPBM. After that, the investigators will investigate the changes of working. Furthermore, based on the neuroimaging technique, the regulatory mechanism of tPBM in intervening older adults will be revealed from the perspective of altered brain functional networks. This study will provide evidence for understanding whether the tPBM has the potentially therapeutic effect on cognitive function for healthy older adults as a non-drug treatment, and further elucidating the potential brain mechanism, which are of great values in solving scientific and clinical practice issues.

NCT ID: NCT03614182 Completed - Clinical trials for Healthy Older Adults

Effects of Simultaneous or Sequential Combination of Physical and Cognitive Training

Start date: August 6, 2018
Phase: N/A
Study type: Interventional

The objective of this study is to investigate psychometric properties of dual-task walking assessments and compare effects of simultaneous or sequential combination of physical and cognitive training on dual-task walking and cognitive performance for community-dwelling healthy older adults.

NCT ID: NCT03234998 Completed - Stroke Clinical Trials

Comparative Efficacy of Two Different Dual-task Balance Interventions

Start date: August 25, 2017
Phase: N/A
Study type: Interventional

The objective of this study is to investigate the effects of two different dual-task balance interventions for stroke patients and older adults.

NCT ID: NCT02839993 Completed - Clinical trials for Healthy Older Adults

tDCS Effects on Associative Learning in Older Adults of Retirement Age

TRAINSTIM2
Start date: April 1, 2016
Phase: N/A
Study type: Interventional

The aim of this study is to investigate whether a tDCS-accompanied training of audio-visual associative memory leads to a performance improvement in healthy older individuals.

NCT ID: NCT02795702 Completed - Clinical trials for Healthy Older Adults

tDCS Effects on Associative Learning in Older Adults of Working Age

TRAINSTIM2
Start date: April 1, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to investigate whether a tDCS-accompanied training of audio-visual associative memory leads to a performance improvement in healthy older individuals.

NCT ID: NCT02794272 Completed - Clinical trials for Healthy Older Adults

tDCS Effects on GABA Concentration and Brain Functional Connectivity in Older Adults Of Working Age

TRAINSTIM1
Start date: April 2016
Phase: N/A
Study type: Interventional

The aim of this study is to investigate whether anodal tDCS over the left M1 leads to a decrease of GABA concentration and alterations of functional brain connectivity in older people, compared to sham tDCS.

NCT ID: NCT02794259 Completed - Clinical trials for Healthy Older Adults

tDCS Effects on GABA Concentration and Brain Functional Connectivity in Older Adults of Retirement Age

TRAINSTIM1
Start date: April 2016
Phase: N/A
Study type: Interventional

The aim of this study is to investigate whether anodal tDCS over the left M1 leads to a decrease of GABA concentration and alterations of functional brain connectivity in older people, compared to sham tDCS.

NCT ID: NCT02346981 Completed - Clinical trials for Healthy Older Adults

Resistance Training and Post-exercise Blood Pressure in Normotensive Older Women

Start date: February 2008
Phase: N/A
Study type: Interventional

The purpose of the present study was to analyze the effect of 12 weeks of resistance training on post-exercise blood pressure (BP) and to to correlate the acute and chronic decrease in blood pressure (BP) following resistance training in normotensive older women. Twenty-eight older women were randomly assigned to a training group (TG) or to a control group (CG). The TG underwent a resistance training program (8 exercises, 2 sets, 10-15 repetitions), while the CG performed stretching exercises (2 sets, 20 s each, 2 nonconsecutive days/week). Both groups performed the intervention for 12 weeks. At baseline and after intervention the subjects were submitted to two sessions: resistance exercise session and control session. In these sessions, BP was obtained in pre and post-sessions. Rest blood pressure were also measure at baseline and after 12 weeks of intervention.