The Effects of Dragon Fruit Consumption on Vascular Function.

Status Completed

Clinical Trial Summary

Native to South America and South East Asia, the dragon fruit (pitaya) has become increasingly popular world-wide due to their vivid hue and bizarre structure. More importantly, their high levels of bioactive phytochemical betalains has sparked considerable scientific interest. Recent findings from in vitro and in vivo animal studies tentatively suggest that betalains may have ameliorative effects on vascular function. This will be a first randomised controlled trial aimed to explore the impact of dragon fruit consumption on blood pressure and other vascular parameters in healthy individuals. The study will feature a randomised, double-blinded, placebo-controlled and crossover design with flow-mediated dilatation (FMD) as primary outcome along with blood pressure and arterial stiffness as secondary outcomes. Cardiovascular biomarkers as well as relevant metabolites will also be determined from blood and urine samples collected from participants.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Healthy Men and Women

Clinical Trial Details

NCT number	NCT03995602
Study type	Interventional
Source	King's College London
Contact
Status	Completed
Phase	N/A
Start date	June 18, 2019
Completion date	January 22, 2020

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