Healthy Men and Women Clinical Trial
Official title:
Absorption, Metabolism and Excretion of Artichoke Polyphenols in Healthy Individuals
A number of studies have reported the presence of polyphenolic compounds in artichokes, being
the most abundant the caffeoylquinic acids (CQAs), which are esters between quinic acid and
the hydroxycinnamate caffeic acid. The fate of artichoke polyphenols in humans after
ingestion is currently unknown. The acute study will provide novel information on the
bioavailability and metabolism of artichoke polyphenols, which will give important insights
to understand the potential health benefits of artichoke consumption.
Health men and women participants (n=8) aged between 18 to 40 years old will be recruited.
Participants will consume a normal ration of artichokes once. The participants will provide
the investigators with urine and blood samples for polyphenol analysis at baseline and at
different time points until 24 hours.
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