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Healthy Individuals clinical trials

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NCT ID: NCT02783456 Completed - Clinical trials for Arterial Hypertension

The Influence of Aircraft Noise Exposure on Renal Hemodynamic in Healthy Individuals

LÄRM
Start date: March 2016
Phase: N/A
Study type: Interventional

Epidemiological studies have found a link between aircraft noise exposure and increased incidence of arterial hypertension and thus cardiovascular disease. The underlying pathophysiological mechanisms are not yet fully understood. The kidney acts as a long-term regulator of blood pressure and controls the extracellular sodium and water balance. Significant renal mechanisms of blood pressure regulation are the renin angiotensin system, renal sympathetic activity and sodium excretion. Animal work and clinical studies show that mental stress affects the renal plasma flow and urinary sodium excretion. The investigators observed a lower sodium excretion in situations of mental stress in subjects at risk for developing arterial hypertension. In healthy volunteers, a 30-minute mental stress test resulted in increased glomerular filtration rate, filtration fraction and an increase in urinary sodium excretion. In this pilot study the investigators analyzed the influence of 30 minutes standardized aircraft noise on renal and central hemodynamics.

NCT ID: NCT02409836 Completed - Healthy Individuals Clinical Trials

A Study to Assess the Ingestion of Dentifrice by Children

Start date: May 1993
Phase: N/A
Study type: Interventional

The objective of this study was to examine the amount of dentifrice ingested and used by various age groups of children.

NCT ID: NCT02101801 Completed - Healthy Individuals Clinical Trials

Urine Drug Levels Related to Source of Water for Irrigation for Vegetable Crops Among Healthy Israeli Volunteers

Start date: September 2014
Phase: N/A
Study type: Interventional

Over 60% of crops in Israel are grown in recycled treated waste water. This study aims to determine whether minute quantities of drugs such as Carbamazepine can be found in individuals who ingest vegetables grown in waste water.

NCT ID: NCT02096796 Completed - Healthy Individuals Clinical Trials

Arm Pump in Motorcross Training

Start date: April 2014
Phase: N/A
Study type: Observational

Arm Pump is a sport specific term drivers use to describe Acute or Chronic Compartment Syndrome of the forearm. Drivers experience pain in the forearms due to increased blood pressure in forearm muscle compartments. No strategies nor methods have been used to diminish the risk to suffer from arm pump within motor cross. This project aims to look at ergonomics of driving and its relationship with the occurrence of arm pump. The investigators will first investigate the experience of motor cross athletes with arm pump through motor cross federations in Belgium and The Netherlands (survey). Two groups of athletes will be selected (20 persons within each group) who will be invited to the motor cross track to investigate their hand grip strength, motor driving position, muscle activity.

NCT ID: NCT02091427 Completed - Healthy Individuals Clinical Trials

Circadian Variation of Cardiac Troponin

Start date: January 2013
Phase: N/A
Study type: Observational

Acute myocardial infarction (AMI) is defined by an increase and/or decrease in the concentration of cardiac troponin, with at least one value above the 99th percentile value of the reference population together with evidence of ischemia. An objective tool to determine the magnitude of the cardiac troponin change is the use of reference change values (RCV). The basis for this tool is that, for a change to be significant, the difference in serial results must be greater than the inherent variation in two test results. The inherent variation of a laboratory test result is composed of analytical and within-subject biological variation. An important requirement to use RCVs is that the concentrations of cardiac troponins fluctuate randomly around a homeostatic set point in cardio-healthy individuals. Verification of this important condition has never been performed, and violation of this condition would preclude the use of RCV's in clinical practice.

NCT ID: NCT01988805 Withdrawn - Healthy Individuals Clinical Trials

Gene Polymorphism Study of Normal Individual Inflammasome Genes

Start date: February 2013
Phase: N/A
Study type: Observational

This study is intended to collect blood from healthy individuals to investigate whether variations in immune-related (inflammasome) genes affect how the immune cells found in the blood can help fight infections and prevent diseases.

NCT ID: NCT01969383 Recruiting - Clinical trials for Healthy Individuals.

Comparative Analysis Between Electrical Muscle Activity In Water And Soil

Start date: April 2013
Phase: N/A
Study type: Interventional

Muscle activity in the aquatic environment was investigated while performing different exercises by electromyography analysis, due to conflicting results in the literature in relation to the floor. This study evaluated and compared the electrical activity of the rectus femoris and biceps femoris, in aquatic method and on the floor, during flexion and knee extension exercises with and without load.

NCT ID: NCT01876160 Completed - Healthy Individuals Clinical Trials

Analysis of Sensory and Motor Thresholds During Transcutaneous Electrical Stimulation in Different Sexes and Ages

Start date: March 2011
Phase: N/A
Study type: Interventional

The sensory and motor perception thresholds can influence the therapeutic effects of Transcutaneous Electrical Nerve Stimulation. This study aimed to determine the threshold of sensory perception and the threshold of motor response in young and elderly subjects of both sexes. Eighty healthy volunteers were evaluated; 40 women and 40 men divided into two equal groups of young and elderly subjects. Half of the individuals in each group were stimulated with 5 and 50Hz frequency, with pulse duration of 20, 100, 400, 1000 and 3000µs applied on the flexor muscle bellies of the wrist and fingers. The threshold of sensory perception was identified as the first sensation of increased current intensity and the threshold of motor response as the minimum muscle contraction detected. The results were submitted to ANOVA test, followed by the Tukey test, with a significance level of 5%.

NCT ID: NCT01872117 Completed - Healthy Individuals Clinical Trials

Assessment of Temperature by Infrared Thermography and Blood Conduction Velocity by Doppler After Applying Shortwave Diathermy and Microwave - Correlations With Cardiovascular and Hemodynamic Parameters

Start date: May 2013
Phase: N/A
Study type: Interventional

The deep heat therapies are increasingly frequent in daily physical therapist for the treatment of musculoskeletal diseases. The use of such procedures is justified by their analgesic, anti-inflammatory, antiespasmolíticos and hiperemiantes. However, studies on the cardiovascular effects of these therapies are still incipient. Therefore, this study has as objectives: map the skin temperature changes in the lower limbs in different areas and positions after applying shortwave diathermy and microwave; assess hemodynamic and autonomic cardiovascular parameters, and investigate the occurrence of changes in conduction velocity superficial blood resulting from the application of these thermal features. The study will be conducted on 40 female volunteers between 18 and 30 years, university, healthy, that fit the inclusion and exclusion criteria of the study. The analysis by infrared thermography will be held in a room with temperature maintained at 23 ± 1°C and humidity average 50%. The volunteers will stay in prone position, with the legs bare, resting for 20 min to stabilize skin temperature with temperature of the room. After this period will be held applying diathermy of shortwave or microwave for 20 minutes at moderate heat on the lower limb regions of the hamstrings and triceps surae in extension and flexion to 180° to 90°. The records beat to beat blood pressure and heart rate to autonomic and cardiovascular hemodynamic evaluation will be performed by means of equipment Finometer (Finapress Medical Systems, Inc.) and electrocardiogram (ADInstruments, Inc.), respectively, before and after application of diathermy. On the other hand, the images will be processed using FLIR ThermoScan and blood flow data will be collected through the Doppler ultrasound. The results will be processed and analyzed using descriptive statistics, submitted to a linear regression model with mixed effects (random effects and fixed), with p≤0.05.

NCT ID: NCT01872091 Enrolling by invitation - Healthy Individuals Clinical Trials

Analysis of Neuromuscular, Circulatory and Biomechanical Responses After Cryotherapy

Start date: May 2013
Phase: N/A
Study type: Interventional

Cryotherapy is a resource applied thermal rehabilitation in order to reduce skin temperature and muscle as well as nerve conduction velocity, and promotes vasoconstriction of arteries and veins resulting in decreased blood flow.