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Healthy Female clinical trials

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NCT ID: NCT05875571 Recruiting - Contraception Clinical Trials

Intravenous Ketorolac Administration to Attenuate Post-procedural Pain Associated With Intrauterine Device Placement

Start date: February 5, 2024
Phase: Phase 4
Study type: Interventional

Intrauterine devices (IUDs) are a popular form of long-acting reversible contraception, with a high efficacy rate and few side effects. The insertion procedure for IUDs can be uncomfortable and painful. Sedation may be needed to improve patient comfort. The use of IUDs is increasing in the adolescent population, but perceived pain is a barrier to placement. Propofol is a commonly used agent for pediatric procedural sedation, but it has no analgesic properties. Ketorolac, a nonsteroidal anti-inflammatory drug, has been shown to reduce pain in adults and improve patient satisfaction when used prior to IUD placement.. The current study aims to determine if ketorolac, given in combination with propofol for IUD placement in adolescents, can improve comfort during placement and reduce pain following the procedure. Enrolled patients will receive ketorolac or placebo, in addition to propofol, for IUD placement. By comparing the outcomes of these two groups of patients, we can gain a better understanding of the optimal approach to sedation for IUD insertion in adolescents.

NCT ID: NCT05706753 Completed - Healthy Female Clinical Trials

A Study of Milvexian in Healthy Adult Females

Start date: January 25, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to measure the effect of milvexian given for approximately 2 weeks on (a) how the liver metabolizes other drugs (in this case one called midazolam), and (b) the pharmacokinetics (the way the body absorbs, distributes, and gets rid of a drug) of an oral contraceptive pill in healthy adult females.

NCT ID: NCT03296098 Suspended - Contraception Clinical Trials

Study of the Safety and Efficacy of Ulipristal Acetate (UPA) Used Daily as a Contraceptive

CCN013B
Start date: December 2020
Phase: Phase 2
Study type: Interventional

This is a Phase IIb multicenter, open-label, non-comparative trial of continuous daily oral 10 mg of ulipristal acetate (UPA) to evaluate its contraceptive efficacy as the primary method of contraception.