Healthy Aging Clinical Trial
Official title:
A Randomized, Double-blind, Placebo Controlled, Cross-over Clinical Trial of Acute Safety and Biological Effects of a Polyphenol Supplement
A randomized, double-blind, placebo controlled, cross-over trial to investigate the effect of the Investigational Product "DailyColors™" (DC) on age-related pathways in adults. The aim of this study is to measure the effects of acute treatment with DC on key pathways relevant to healthy ageing using blood biomarkers. Based on power calculations a sample size of 20, is sufficient to detect an effect size of 0.46 at a power > 90%. To account for dropout the investigators will include 26 subjects in total.
Aims: The aim of this study is to measure the effects of acute treatment with DC on key pathways relevant to healthy ageing using blood biomarkers. Hypotheses: There will be preliminary evidence that the IP has positive clinical effects on biologically relevant pathways related to healthy aging of brain and muscle including blood markers of inflammation, oxidative stress markers, and trophic factors. Design: A randomized, double-blind, placebo controlled, cross-over trial to investigate the effect of the Investigational Product (DailyColors™) on age-related pathways in adults. Participants will receive DailyColors™ or placebo for a week, then one week wash-out, and then placebo/Dailycolors™ for a week, in random order. In addition, participants will be invited to participate in an open-label extension study for 3 months. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05596474 -
Effect of Beet-root Juice and PBM Treatments on Muscle Fatigue
|
N/A | |
| Active, not recruiting |
NCT05203848 -
Community Dance Program (CDP) for Older Adults
|
Phase 1 | |
| Not yet recruiting |
NCT06455982 -
Reduced Carbohydrates + Ketogenic Supplement on Energy Metabolism
|
N/A | |
| Completed |
NCT04084457 -
Investigating the Effects of Daily Consumption of Blueberry (Poly)Phenols on Vascular Function and Cognitive Performance
|
N/A | |
| Recruiting |
NCT05006261 -
A Mobile Tai Chi Platform for Fall Prevention in Older Adults - Phase II
|
N/A | |
| Active, not recruiting |
NCT04262674 -
Non-invasive, Wearable Multi-parameter System for the Early Prediction of Cognitive Decline and Dementia in Older Adults
|
N/A | |
| Completed |
NCT02218411 -
Video-supported Group-based Otago Exercise Programme on Physical Performance in Older Adults.
|
Phase 1 | |
| Active, not recruiting |
NCT05961319 -
Smart Home Technologies for Assessing and Monitoring Frailty in Older Adults
|
||
| Completed |
NCT05213091 -
The Effect of Otago Exercises in the Elderly
|
N/A | |
| Active, not recruiting |
NCT04904068 -
Functional Neuroimaging in Parkinson's Disease
|
||
| Completed |
NCT04348162 -
Food Anthocyanins and Flavanols as a Strategy for a Healthy Ageing: Cardiovascular Health and Cognitive Performance
|
N/A | |
| Completed |
NCT05941143 -
Effect of Mindfulness on EEG Brain Activity for Cognitive and Psychological Well-being in the Elderly
|
N/A | |
| Completed |
NCT06022094 -
Effect of a Two-month Carbohydrate-restricted Diet on Energy Metabolism in a Seniors' Residence
|
N/A | |
| Active, not recruiting |
NCT06162871 -
Social Participation and Healthy Aging
|
N/A | |
| Completed |
NCT05207501 -
Effects of Different Moderate-intensity Exercise Methods on Health in the Elderly
|
N/A | |
| Recruiting |
NCT04986787 -
Novel, Individualized Brain Stimulation, Network-based Approaches to Improve Cognition
|
N/A | |
| Completed |
NCT05933798 -
China Pilot of ICOPE (Integrated Care for Older People) in Chaoyang
|
N/A | |
| Recruiting |
NCT05394363 -
Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents
|
||
| Completed |
NCT04786665 -
Strawberries, Cognition, and Vascular Health
|
N/A | |
| Completed |
NCT05290571 -
Modified Otago Exercise Program on Balance Performance
|
N/A |