The Impact of Watermelon Juice on Blood Pressure

Status Active, not recruiting

Clinical Trial Summary

L-citrulline is found naturally in watermelon. Recently interest has increased for this amino acid due to potential health benefits. Notably, L-citrulline has the potential to lead to dilation of blood vessels due to its involvement in the production of nitric oxide. The study will be an acute single blind, randomised controlled, crossover intervention study in healthy, young volunteers. Participants receive either the test watermelon drink or control drink (water). Blood samples and vascular measures (by a single-cuff based method) will be measured at baseline. Vascular measures will be repeated at 15-minute intervals between 0-2 hours and a second blood sample will be drawn at 1.5 hours to coincide with the estimated peak plasma L-citrulline. Citrulline, arginine and nitric oxide metabolites will be measured in the blood samples.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Healthy Aging

Clinical Trial Details

NCT number	NCT04328311
Study type	Interventional
Source	University of Reading
Contact
Status	Active, not recruiting
Phase	N/A
Start date	January 8, 2020
Completion date	December 30, 2022

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