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Sensory Study: Taste and Tongue Biology — SweetTaste  

Healthy Adults Clinical Trial

Official title:
Sensory Study: Taste and Tongue Biology

Clinical Trial Summary

Researchers will investigate the correlation between a) self-reported dietary intake of foods and beverages, b) intensity of sucrose stimuli, and c) liking rating of sweet stimuli, with the relative expression of the taste receptor genes from human fungiform papillae (TAS1R2 and TAS1R3). * This research will provide new information on how sweet taste perception is regulated. - The hypothesis: Greater dietary consumption of sugar and sweet foods is associated with reduced expression of the sweet taste receptors. - The results of this study could help to identify pathways to help modify sweet taste perception by uncovering this mechanism. Participants will sample solutions prepared with sweet ingredients, provide salivary DNA, and collect fungiform papillae. This will allow researchers and investigators to compare the relationship between the sweetness of stimuli, genetic differences in sweet taste receptors, and expression levels of sweet taste receptor genes.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05985928
Study type Observational
Source University of Massachusetts, Amherst
Contact
Status Completed
Phase
Start date March 20, 2023
Completion date May 20, 2023
View Details
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