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Healthy Adult clinical trials

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NCT ID: NCT03827005 Completed - Healthy Adult Clinical Trials

L-arginine Supplementation and Resistance Exercise

Start date: July 16, 2016
Phase: N/A
Study type: Interventional

The purpose of this study was to examine the acute endothelial, cardiovascular, and performance responses to L-arginine by assessing flow-mediated dilation (FMD) and heart rate variability (HRV) both before and after resistance exercise to fatigue. Thirty (15 male, 15 female) physically active participants volunteered for a randomized, cross-over, double-blind, placebo- controlled clinical trial. Participants completed five sets of elbow extension-flexion exercise after consumption of either 3 g of placebo or 3 g L-arginine.

NCT ID: NCT02257151 Completed - Healthy Adult Clinical Trials

Study to Evaluate the Safety, Pharmacokinetics and Target Engagement of BMS-986142 in Healthy Subjects

Start date: September 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, pharmacokinetics, and target engagement of BMS-986142 in healthy subjects.

NCT ID: NCT01506752 Completed - Healthy Adult Clinical Trials

A Bioequivalence Study Comparing Improved Versus Current Orally Disintegrating E2020 10 mg Tablet in Healthy Japanese Adult Males

Start date: July 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the bioequivalence of improved and current orally disintegrating E2020 10 mg tablets as a single dose in Japanese healthy adult males for each of two administration methods (with/without water).

NCT ID: NCT01506739 Completed - Healthy Adult Clinical Trials

A Bioequivalence Study of Film-coated Tablet and Dry Syrup 1% Form for E2020 in Healthy Japanese Adult Males

Start date: March 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to confirm bioequivalence between E2020 dry syrup 1% form (0.5 g), given either with 200 mL of water or suspended in 20 mL of water, and E2020 film-coated tablet (5 mg) in Japanese healthy adult males.

NCT ID: NCT01274130 Completed - Healthy Adult Clinical Trials

Investigatory Study of Metformin's Pharmacokinetics, Pharmacodynamics and Drug Drug Interactions Classifying the Group by MATE1 Genotype in Healthy Volunteers

Start date: December 2010
Phase: N/A
Study type: Interventional

This is the investigatory study to find out metformin's pharmacokinetics, pharmacodynamics and drug-drug interactions classifying the group by MATE1 genotype in healthy volunteers. The investigators will apply ranitidine and verapamil to the drug interaction study of metformin.

NCT ID: NCT00400309 Completed - Healthy Adult Clinical Trials

Safety of REPEVAX® Given One Month After REVAXIS®

Start date: June 2006
Phase: Phase 3
Study type: Interventional

Primary objective: - To describe the safety profile of a Tetanus, Diphtheria, Poliomyelitis and Pertussis vaccine (REPEVAX®) when administered as a pertussis booster 1 month after a Tetanus, Diphtheria, Poliomyelitis vaccine (REVAXIS®) as compared to the safety profile of REPEVAX® administered one month after Placebo. Secondary objectives: - To describe the safety of Td-IPV vaccine (REVAXIS®) or Placebo administered to healthy adults. - To describe the safety of TdaP-IPV vaccine (REPEVAX®) administered one month after Td-IPV vaccine (REVAXIS®) or one month after Placebo.