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Healthy Adult clinical trials

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NCT ID: NCT06171880 Completed - Healthy Adult Clinical Trials

To Evaluate the Safety and Pharmacokinetic Characteristics After the Administration of JC-001 and JLP-1901

Start date: February 15, 2022
Phase: Phase 1
Study type: Interventional

To evaluate the safety and pharmacokinetic characteristics after the administration of JC-001 and JLP-1901

NCT ID: NCT06169059 Completed - Healthy Adult Clinical Trials

To Evaluate the Safety and Pharmacokinetic Characteristics After Multiple Administration of JC-013 and JLP-2004

Start date: October 5, 2023
Phase: Phase 1
Study type: Interventional

To evaluate the safety and pharmacokinetic characteristics after multiple administration of JC-013 and JLP-2004

NCT ID: NCT06165965 Completed - Healthy Adult Clinical Trials

To Evaluate the Safety and Pharmacokinetic Characteristics After the Administration of JT-001, JT-002 and JLP-2008

Start date: May 3, 2022
Phase: Phase 1
Study type: Interventional

To evaluate the safety and pharmacokinetic characteristics after the administration of JT-001, JT-002 and JLP-2008

NCT ID: NCT05688566 Completed - Healthy Adult Clinical Trials

Biomechanical Characteristics of Lower Extremity During Pinnacle Trainer With Different Pedal Angles

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

To investigate the effects of pedal degree on the biomechanical characteristics of the healthy adults' lower limbs during stepping on the pinnacle trainer.The purpose of this study are compare the biomechanical characteristics of low limbs at different angle of pedal during stepping on Pinnacle trainer. The investigators hope to provide this outcome to therapists can make the rehabilitation training more effective and delay the disease progression of KOA patients.

NCT ID: NCT05408572 Completed - Healthy Adult Clinical Trials

Study of SON-1010 (IL12-FHAB) in Healthy Adults

Start date: July 27, 2022
Phase: Early Phase 1
Study type: Interventional

SB102 is a randomized, double-blind, single center, placebo-controlled study in healthy adults starting with sentinel participants at each dose level to carefully assess the safety, tolerability, PK, and PD of SON-1010.

NCT ID: NCT04027218 Completed - Venipuncture Clinical Trials

Clinical Trial to Assess the Effectiveness of Applying Dry Local Heat and/ or High Tourniquet Pressure for Venipuncture.

ECYPVEN-H/17
Start date: July 9, 2017
Phase: N/A
Study type: Interventional

Low level intervention health products clinical trial, fourth phase, non-commercial research. Dissertation of COMPLUTENSE UNIVERSITY of Madrid. Principal Investigator of this clinical trial: Ms. LETICIA CARMEN SIMÓN LÓPEZ Collaborative investigators: Dr. DOLORES OCHOA-MAZARRO (principal investigator of bioequivalence clinical trial), and Sir. SERGIO LUQUERO-BUENO (collaborative researcher) The setting is Clinical trials Unit of Clinical Pharmacology Department. LA PRINCESA HOSPITAL of Madrid. Research Ethical Committee of LA PRINCESA HOSPITAL of Madrid. Any person will monitor this clinical trial because the sponsor and principal researcher are the same person. Nevertheless, an adherence to this protocol will ensure by principal researcher and co-researchers. The three interventions are: 1. To Apply local dry heat. 2. To apply high tourniquet pressure. 3. To apply both of them. (Dry heat and high pressure) The common comparator: Current Clinical practice for peripheral venous catheterization. The main hypothesis: The number of attempts of success venipuncture at first time are influenced by any of the interventions applied before. The main goal: To identify the most effective intervention of applying dry local heat and/or high tourniquet pressure in relation of number success venipuncture attempts, compared to current clinical practice. Design: An experimental, randomized study which is controlled with current clinical practice to insert a peripheral vein catheter. It is an incomplete cross-over clinical trial, with three arms which are involved interventions and a common comparator. Population: Adult healthy subjects. Sample size: It is required to enroll 54 subjects with a 95% of level of confidence and 80% level of power. Main variable: Succeed peripheral vein catheter insertion at first attempt. Effectiveness assessment: The optimal effectiveness is considered when vein cannulation success at first attempt exceeds 95% applying any of the interventions. Planned date to address: It is planned to carry out around June and/or July of 2017 for the main variable.

NCT ID: NCT03827005 Completed - Healthy Adult Clinical Trials

L-arginine Supplementation and Resistance Exercise

Start date: July 16, 2016
Phase: N/A
Study type: Interventional

The purpose of this study was to examine the acute endothelial, cardiovascular, and performance responses to L-arginine by assessing flow-mediated dilation (FMD) and heart rate variability (HRV) both before and after resistance exercise to fatigue. Thirty (15 male, 15 female) physically active participants volunteered for a randomized, cross-over, double-blind, placebo- controlled clinical trial. Participants completed five sets of elbow extension-flexion exercise after consumption of either 3 g of placebo or 3 g L-arginine.

NCT ID: NCT02257151 Completed - Healthy Adult Clinical Trials

Study to Evaluate the Safety, Pharmacokinetics and Target Engagement of BMS-986142 in Healthy Subjects

Start date: September 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, pharmacokinetics, and target engagement of BMS-986142 in healthy subjects.

NCT ID: NCT01506752 Completed - Healthy Adult Clinical Trials

A Bioequivalence Study Comparing Improved Versus Current Orally Disintegrating E2020 10 mg Tablet in Healthy Japanese Adult Males

Start date: July 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the bioequivalence of improved and current orally disintegrating E2020 10 mg tablets as a single dose in Japanese healthy adult males for each of two administration methods (with/without water).

NCT ID: NCT01506739 Completed - Healthy Adult Clinical Trials

A Bioequivalence Study of Film-coated Tablet and Dry Syrup 1% Form for E2020 in Healthy Japanese Adult Males

Start date: March 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to confirm bioequivalence between E2020 dry syrup 1% form (0.5 g), given either with 200 mL of water or suspended in 20 mL of water, and E2020 film-coated tablet (5 mg) in Japanese healthy adult males.