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Headache clinical trials

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NCT ID: NCT05967442 Completed - Migraine Clinical Trials

Magnesium Versus Prochlorperazine Versus Metoclopramide for Migraines

MAGraine
Start date: August 23, 2019
Phase: Phase 3
Study type: Interventional

This investigation describes a proposed clinical trial that will evaluate the relative efficacy of intravenous magnesium sulfate for the treatment of migraine compared to intravenous metoclopramide (Reglan) and intravenous prochlorperazine (Compazine) in the treatment of acute headache and migraine in adult patients. The ultimate objective will be clinical application of these drugs in the emergency department for the treatment of acute headache and migraine. The two phenothiazines (metoclopramide and prochlorperazine) have been routinely utilized in the treatment of acute headache and migraine in the emergency department setting. Per the 2017 American Headache Society guidelines, both intravenous metoclopramide and intravenous procholorperazine are recommended as "clinicians should offer" agents with level B evidence. Of note, there are no agents with level A evidence purported by this guideline for acute management of migraine. The same guideline offers "no recommendation can be made regarding the role of intravenous magnesium for adults who present to the ED with acute migraine. However intravenous magnesium may be of benefit to patients who present with migraine with aura." Multiple trials have evaluated intravenous magnesium's safety and efficacy in the management of acute migraine. These have demonstrated the tolerability of intravenous magnesium on a with breadth of patients. Most commonly the primary adverse event was flushing which self-resolved. No cases of hypotension were reported. None of these study agents have been withdrawn from the market.

NCT ID: NCT05939583 Completed - Clinical trials for Cervicogenic Headache

Effect of Shock Wave Therapy on Upper Trapezius Trigger Points in Patients With Cervicogenic Headache.

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

Control group will receive US, TENS, IR and exercises. The treatment group will receive the same program in addition to shock waves therapy. Patients will receive 3 sessions per week for 4 weeks.

NCT ID: NCT05883319 Completed - Exercise Clinical Trials

The Effect Of Cervical Mobilization And Clinical Pilates in Cervicogenic Headache

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Cervicogenic headache (CH) arises from cervical region problems. Various physiotherapy methods such as manual therapy approaches and exercise training are used in the treatment of CH. The aim of our study is to investigate cervical mobilization and clinical Pilates exercises on pain, muscle stiffness, head and neck blood flow in CH. Including individuals diagnosed with CH in the study. Those to be included in the study will be divided into 3 groups by a simple method. Demographic information of the individuals, age, height, weight, Body Mass Index (BMI), gender, educational status, occupation, marital status, smoking, alcohol use will be recorded. In evaluations about pain before treatment; pain intensity, pain frequency, duration and characteristics will be evaluated with Visual Analog Scale (VAS). In addition, analgesic use (frequency, amount) in headache situations will be recorded. Migraine Disability Assessment Scale (MIDAS) will be used to determine the effect of headache on quality of life. Disability Index will be used in the assessment of functional desire, and Postur Screen mobile application will be used in the assessment of posture. Range of motion(ROM) of all neck joint movements will be evaluated by CROM goniometer, deep neck flexor muscle strength by Pressure Biofeedback Unit (PBU), sternocleidomastoid(SKM), suboccipital and upper trapezius muscle stiffness myotonometer, and head-neck artery flow volume will be evaluated by Doppler ultrasound. Cervical mobilization methods will be applied to the 1st group, clinical pilates applications to the 2nd group, clinical pilates with cervical mobilization will be applied to the 3rd group for 3 days / week for 6 weeks. All evaluations were completed again after the 3rd week and after the treatment. After the obtained results are obtained, the literature will be discussed.

NCT ID: NCT05865808 Completed - Clinical trials for Cervicogenic Headache

Effects of Sustained Natural Appophyseal Glide Versus Rocababo 6x6 Program in Subjects With Cervicogenic Headache.

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effects of TMJ directed treatment approach using the Rocabado 6x6 program in patients with cervicogenic headache on the intensity of headache, function of the neck, and quality of life and compare its effectiveness with headache SNAGs which have been proven very effective in treatment of cervicogenic headache.

NCT ID: NCT05865613 Completed - Fatigue Clinical Trials

Effect of Electromagnetic Therapy on Patients With Chronic Rhinosinusitis.

Start date: December 15, 2021
Phase: N/A
Study type: Interventional

This study aimed to evaluate the efficacy of Pulsed electromagnetic field (PEMF) for Chronic sinusitis in a randomized, double-blind, placebo-controlled trial.

NCT ID: NCT05861817 Completed - Fatigue Clinical Trials

Effect of Low Level Laser Therapy in Patients With Chronic Rhinosinusitis.

Sinusitis
Start date: January 18, 2022
Phase: N/A
Study type: Interventional

This study aimed to evaluate the efficacy of low-level laser therapy (LLLT) for Chronic sinusitis in a randomized, double-blind, placebo-controlled trial.

NCT ID: NCT05853900 Completed - Migraine Clinical Trials

Study of Two Digital Therapeutics for the Prevention of Episodic Migraine

ReMMi-D
Start date: March 28, 2023
Phase: Phase 3
Study type: Interventional

Randomized study of two digital therapeutics for the prevention of episodic migraine

NCT ID: NCT05849545 Completed - Clinical trials for Cervicogenic Headache

Effects of Garston Tool and Neuromuscular Reeducation in Cervical Headache

Start date: March 10, 2021
Phase: N/A
Study type: Interventional

Patients suffering from Cervicogenic headache have restricted range of motion and pain which in turn causes functional disability and reduced quality of life. The aim of this research was to determine the effects of Graston technique to improve range of motion, function, and reduction of pain and in patients having Cervicogenic headache

NCT ID: NCT05843760 Completed - Migraine Clinical Trials

Headache in Undergraduate Students and Biopsychosocial Status

Start date: May 4, 2023
Phase:
Study type: Observational [Patient Registry]

The primary aim of this study was to determine the prevalence of headache in undergraduate students. The frequency, duration, localizations and symptoms of headache will be determined with the information obtained as a result of the forms filled in by the participants. The second aim of this study is to examine the effects of headache on physical, social and psychological status in undergraduate student(participants) from a biopsychosocial perspective.

NCT ID: NCT05839496 Completed - Headache Clinical Trials

Cervical Stabilization Training on Individuals With Headache

Start date: January 2, 2019
Phase: N/A
Study type: Interventional

Headache is a common health problem. The most common headaches worldwide are migraine, tension-type headache (TTH), and cervicogenic headache (CGH). Due to the close anatomical relationship between the head and the cervical region, neck pain accompanies these headaches. The effects of cervical stabilization training including all of the cervical regions, thoracic regions, and the upper extremities in individuals with headaches are not yet known.