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Clinical Trial Summary

The purpose of this study is to determine if intranasal (IN) Ketorolac in combination with oral Prochlorperazine and Diphenhydramine is non-inferior to current migraine management which involves use of intravenous (IV) Ketorolac and oral adjuncts Prochlorperazine and diphenhydramine for reducing pain intensity in children with migraine headaches. The investigators hypothesize that IN ketorolac combined with these oral adjuncts is non-inferior to IV ketorolac and oral adjuncts in reducing acute migraine headache pain by a minimum clinically significant difference within 60 minutes of administration.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06083571
Study type Interventional
Source Washington University School of Medicine
Contact Carlee Lenehan, MD
Phone 3529018388
Email carleel@wustl.edu
Status Not yet recruiting
Phase Phase 2
Start date January 1, 2024
Completion date January 1, 2026

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