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Headache Disorders clinical trials

View clinical trials related to Headache Disorders.

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NCT ID: NCT04970355 Completed - Cluster Headache Clinical Trials

Efficacy of Erenumab in Chronic Cluster Headache

CHERUB01
Start date: December 2, 2021
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to evaluate the efficacy of erenumab in participants with chronic cluster headache.

NCT ID: NCT04939922 Recruiting - Fibromyalgia Clinical Trials

China Headache Registry Study

CHRS
Start date: June 12, 2017
Phase:
Study type: Observational [Patient Registry]

In the Chinese Headache and Vertigo Registration Study, patients aged 4-99 years with headache (primary headache and secondary headache such as migraine and tension type headache), vertigo (vertigo diseases such as vestibular migraine) and chronic pain (fibromyalgia and other diseases) were collected. The biomarkers, imaging features, right-to-left shunt of the heart (lung), genetic characteristics, treatment, and outcome (in relation to other diseases) of headache-related diseases were studied, and long-term follow-up was planned.

NCT ID: NCT04936321 Active, not recruiting - Insomnia Clinical Trials

Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial

I-SPY-RCT
Start date: October 1, 2021
Phase: N/A
Study type: Interventional

Insomnia is a common comorbidity among adolescents with migraine. This randomized controlled clinical trial aims to determine efficacy of cognitive-behavioral therapy (CBT) for insomnia, as well as the combined effect of CBT insomnia and pain interventions, on reducing insomnia symptoms and headache-related disability in adolescents with migraine. The long-term goal is to offer effective, tailored self-management interventions that can address migraine and co-morbid sleep problems in adolescence and disrupt a cycle of persistent, disabling migraine from continuing into adulthood.

NCT ID: NCT04891848 Completed - Headache Disorders Clinical Trials

Assessment of Inflammation in Primary Headaches

Start date: May 1, 2018
Phase:
Study type: Observational [Patient Registry]

Headache is the most common neurological complaint accounting for % 1 to % 4 in the emergency department (ED).Every year, nearly one million people with headache attacks have been consulted by healthcare professionals at the emergency room in the United States.The International Classification of Headache Disorders (ICHD) divided headaches into two main groups: primary headaches and secondary headaches. The vast majority of cases who presented with acute headache attack in ED had a diagnosis of primary headache disorders (tension- type headache, migraine, cluster- type headache, and other primary headaches). However, secondary headache is often associated with underlying intracranial pathologies, and noted in % 10 of cases in emergency rooms. Despite the frequent presence of primary headaches, limited time setting and busy periods of medical assessment, leading diagnostic and therapeutic options due to the pathophysiological factors to be overlooked. To date, no study in the emergency care setting has explored the role of inflammation in patients with acute migraine and TTH. Investigators aimed to explore inflammatory markers [white blood cells (WBC), neutrophil, lymphocyte, platelet, neutrophil / lymphocyte ratio (NLR), and platelet / lymphocyte ratio (PLR)] in complete blood count (CBC) among MA, MO, and TTH participants who admitted to ED with acute headache attack and healthy volunteers.

NCT ID: NCT04877561 Not yet recruiting - Headache Disorders Clinical Trials

Test-Retest Reliability of the German Version of the Headache Disability Questionnaire (HDQ).

Start date: June 1, 2021
Phase:
Study type: Observational

a translated and cultural adapted version of the HDQ will be tested on two occasions with headache patients who are currently in physiotherapeutic treatment due to their headache condition

NCT ID: NCT04765501 Recruiting - Headache Clinical Trials

Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Impact Questionnaire

Start date: March 1, 2021
Phase:
Study type: Observational

The purpose of this study was to investigate cultural adaptation, reliability and validity of the Turkish version of the Headache Impact Questionnaire (HIQ).

NCT ID: NCT04736654 Recruiting - Headache Clinical Trials

Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Disability Questionnaire

Start date: March 1, 2021
Phase:
Study type: Observational

The purpose of this study was to investigate cultural adaptation, reliability and validity of the Turkish version of the Headache Disability Questionnaire (HDQ).

NCT ID: NCT04715685 Recruiting - Migraine Clinical Trials

Mind Body Balance for Pediatric Migraine

Start date: March 9, 2021
Phase: N/A
Study type: Interventional

This study uses a factorial research design to evaluate a nurse delivered mind body intervention using different doses of 3 treatment components to determine the optimized treatment for headache day reduction.

NCT ID: NCT04696627 Completed - Clinical trials for Post-Dural Puncture Headache

Long-term Complications of Unintentional Dural Puncture During Labour Epidurals and Epidural Blood Patch.

Start date: February 12, 2021
Phase:
Study type: Observational

The investigators plan to evaluate long-term consequences of unintentional dural puncture in women who had this complication during labor epidural insertion at Mount Sinai Hospital. A dural puncture is the perforation of the dura mater (one of the layers protecting the brain and the spinal cord) by the needle that is used to find and place a catheter in the epidural space. A puncture will cause a leakage of cerebrospinal fluid through the dura that results in an acute and usually self-limited headache in half of patients who have this complication. The usual treatment for this complication is conservative with the use of oral medications like acetaminophen, anti-inflammatory and narcotics. In the severely symptomatic patient, the injection of blood in the epidural space is a more invasive approach performed to "patch" the hole that was created in the dura (epidural blood patch). The objective is to determine whether or not there is a risk of developing long-term effects from the unintentional dural puncture and its treatment by epidural blood patch by comparing women who had a dural puncture during their labour epidural insertion with or without an epidural blood patch with women who received an epidural but did not have a dural puncture during the same period of time. The hypothesis is that women who had unintentional dural punctures during epidural insertion will develop long-term effects such as chronic headache, chronic backache, chronic auditory or visual disturbances and chronic disability more frequently than women who received an epidural but did not sustain a dural puncture. The investigators also hypothesize that the use of epidural blood patch may change the course of these complications.

NCT ID: NCT04352218 Not yet recruiting - Headache Clinical Trials

Safety Profile of PETALO CVS in the Treatment of Non-thrombotic Internal Jugular Vein Stenosis and Chronic Headache

PETALO
Start date: September 2020
Phase: Phase 2
Study type: Interventional

The purpose of the study is to assess, as first stage, the safety profile of an innovative venous- oriented device (Petalo CVS) in the treatment of patients with non-thrombotic internal jugular vein stenosis and chronic headache resistant to best medical therapy. After Stage 1, a second stage will be conducted to evaluate the preliminary efficacy.