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Head and Neck Cancer clinical trials

View clinical trials related to Head and Neck Cancer.

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NCT ID: NCT00337129 Completed - Clinical trials for Head and Neck Cancer

S0618 E7389 in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

Start date: May 2006
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy, such as E7389, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase II trial is studying how well E7389 works in treating patients with metastatic or recurrent head and neck cancer.

NCT ID: NCT00334997 Completed - Clinical trials for Head and Neck Cancer

Endoscopic Surgery or Radiation Therapy in Treating Patients With Stage 0, Stage I, or Stage II Laryngeal Cancer of the Glottis

Start date: September 2005
Phase: Phase 2
Study type: Interventional

RATIONALE: Endoscopic surgery is a less invasive type of surgery for laryngeal cancer and may have fewer side effects and improve recovery. Radiation therapy uses high-energy x-rays to kill tumor cells. It is not yet known whether endoscopic surgery is more effective than radiation therapy in treating laryngeal cancer of the glottis. PURPOSE: This randomized phase II trial is studying endoscopic surgery to see how well it works compared with radiation therapy in treating patients with stage 0, stage I, or stage II laryngeal cancer of the glottis.

NCT ID: NCT00333099 Completed - Clinical trials for Head and Neck Cancer

INEC Study: Immuno-modulating Enteral Nutrition in Cancer

Start date: May 2006
Phase: Phase 4
Study type: Interventional

The aim of this study is to investigate if enteral immunonutrition of head and neck or esophageal cancer patients, using an arginine, omega 3 fatty acid, nucleotides-enhanced diet [Impact (R), Novartis] versus a standard enteral nutrition (control, Novartis), could improve clinical outcomes (mucositis frequency, treatment tolerance), nutritional and immune status, and life quality parameters.

NCT ID: NCT00332865 Completed - Clinical trials for Head and Neck Cancer

Swallow Exercise as Prophylaxis of Dysphagia After Radiotherapy

Start date: June 2006
Phase: Phase 1/Phase 2
Study type: Interventional

Background: Dysphagia is a common side effect after radiotherapy for haed and neck cancer patients. It may be worsened by immobility of the throat during tube feeding. Hypothesis: Exercises may prevent or reduce late dysphagia. Method: Phase I study to identify the tolerated intensity of exercises and establish the method of measuring training intensity and dysphagia measurement. Endpoint: Objective dysphagia using VF and FEESST. The HN swallowing and HN pain endpoint of EORTC H&N35 questionnaire. Weight loss, duration of tube feeding.

NCT ID: NCT00329589 Completed - Clinical trials for Head and Neck Cancer

A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients

Start date: September 2005
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety of Velcade when used with chemoradiation in cancer patients.

NCT ID: NCT00318890 Completed - Clinical trials for Head and Neck Cancer

Cisplatin and Docetaxel Plus Docetaxel and Radiotherapy With Amifostine for Squamous Cell Carcinoma of the Head and Neck

Start date: October 2002
Phase: Phase 1/Phase 2
Study type: Interventional

This trial seeks to accomplish both local and regional control of head and neck cancer and reduce systemic metastatic disease. To do this, patients will received chemotherapy followed by chemotherapy and radiation (given together) with an escalating dose of docetaxel.

NCT ID: NCT00316823 Completed - Clinical trials for Head and Neck Cancer

Genetic Analysis in Diagnosing Thyroid Cancer in Patients With Thyroid Nodules

Start date: July 2005
Phase: N/A
Study type: Interventional

RATIONALE: Finding genetic markers for thyroid cancer in a biopsy specimen may help doctors diagnose thyroid cancer. PURPOSE: This clinical trial is studying how well genetic analysis works in diagnosing thyroid cancer in patients with thyroid nodules.

NCT ID: NCT00313027 Completed - Clinical trials for Head and Neck Cancer

Cervical Nodal Mets in Squamous Cell Carcinoma of H&N - MRI, FDG-PET, & Histopathologic Correlation

Start date: November 2002
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the value of novel non-invasive medical imaging methods for detecting the spread of head and neck squamous cell carcinoma to the lymph nodes in the neck by comparing their results to findings at the time of surgery.

NCT ID: NCT00310115 Completed - Lung Cancer Clinical Trials

Motivational Counseling in Preventing Smoking Relapse After Pregnancy in Pregnant Women Who Quit Smoking During Pregnancy

Start date: April 2002
Phase: N/A
Study type: Observational

RATIONALE: Motivational counseling may help prevent pregnant women from smoking again after pregnancy. PURPOSE: This randomized clinical trial is studying three different types of counseling to see how well they work in preventing smoking relapse after pregnancy in pregnant women who quit smoking during pregnancy.

NCT ID: NCT00304278 Completed - Clinical trials for Head and Neck Cancer

Study of RADPLAT and Tarceva in Locally Advanced Head and Neck Squamous Cell Carcinoma (SCCA)

Start date: March 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and effectiveness of treatment with Tarceva (Erlotinib) and RADPLAT (RADiation and intraarterial cisPLATin) for patients with Head and Neck cancer