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Head and Neck Cancer clinical trials

View clinical trials related to Head and Neck Cancer.

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NCT ID: NCT01044433 Completed - Clinical trials for Head and Neck Cancer

Capecitabine and Lapatinib Ditosylate in Treating Patients With Squamous Cell Cancer of the Head and Neck

Start date: October 2009
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy, such as capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Lapatinib ditosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving capecitabine together with lapatinib ditosylate may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving capecitabine and lapatinib ditosylate together works in treating patients with squamous cell cancer of the head and neck.

NCT ID: NCT01036412 Completed - Clinical trials for Head and Neck Cancer

Chlorhexidine Gel Therapy for Cariogenic Oral Microflora

Start date: December 2009
Phase: Phase 1
Study type: Interventional

The goal of this clinical research study is to find out if 1% chlorhexidine gluconate gel will decrease the amount of bacteria that causes tooth decay. Whether the gel is acceptable to patients will also be studied.

NCT ID: NCT01032096 Completed - Clinical trials for Head and Neck Cancer

The Physiological Response to Routine Head and Neck Cancer Surgery

Start date: May 2009
Phase: N/A
Study type: Observational

The main objective of this pilot study is to observe and document the range of changes in the blood concentrations of certain hormones, inflammatory chemicals and immune chemicals in response to the stimulus of Head and Neck cancer

NCT ID: NCT01030497 Completed - Clinical trials for Head and Neck Cancer

Detection of Cervical Lymph Node Metastases With a High-Resolution Positron Emission Tomography (PET) Imaging System

Start date: December 2009
Phase: N/A
Study type: Observational

The goal of this clinical research study is to learn if using the PEMFlex Solo II, a high-resolution camera for PET scan imaging, on an area of the body that has, or is suspected to have cancer will give researchers the same or better information about the disease compared to the images taken with a routine PET/CT. Researchers will compare the images taken using the PEMFlex Solo II to the images taken during your scheduled routine PET/CT scan, as well as any additional routine CT scan(s), magnetic resonance imaging (MRI) scan(s), and/or ultrasound image(s) you may have had within the last 30 days or may have in the next 30 days.

NCT ID: NCT01024101 Completed - Clinical trials for Head and Neck Cancer

Early Phase II Study of Weekly Paclitaxel (BMS-181339) in Patient With Advanced or Recurrent Head and Neck Cancer

Start date: January 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and the safety of paclitaxel given weekly in patients with advanced or recurrent head and neck cancer

NCT ID: NCT01016769 Completed - Clinical trials for Head and Neck Cancer

Temsirolimus + Weekly Paclitaxel + Carboplatin for Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC)

Start date: November 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to find out the good and bad effects that occur when temsirolimus is added to standard chemotherapy with carboplatin and paclitaxel.

NCT ID: NCT01015963 Completed - Breast Cancer Clinical Trials

Studying DNA in Tissue Samples From Caucasian and African-American Cancer Patients Who Received Docetaxel on Clinical Trial CLB-9871

Start date: October 2008
Phase: N/A
Study type: Observational

This research trial studies deoxyribonucleic acid (DNA) in blood samples from Caucasian and African-American cancer patients who received docetaxel on clinical trial CLB-9871. Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors learn more about how docetaxel is used by the body.

NCT ID: NCT00995319 Completed - Clinical trials for Head and Neck Cancer

Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area

Start date: January 2008
Phase: N/A
Study type: Observational

The purpose of this clinical investigation is to evaluate acute and longlasting side effects in patients undergoing radiotherapy for cancer treatment in the head and neck area.

NCT ID: NCT00984074 Completed - Clinical trials for Head and Neck Cancer

MRI Mapping in Planning Radiation Therapy to the Base of Skull and Brain in Patients With Nonmetastatic Head and Neck Cancer

Start date: October 2008
Phase:
Study type: Observational

RATIONALE: Diagnostic procedures, such as specialized types of magnetic resonance imaging (MRI), may help in planning radiation therapy that does less damage to normal tissues. PURPOSE: This phase I trial is studying using functional MRI to see how well it works in planning radiation therapy in patients undergoing radiation therapy to the base of the skull and/or brain for nonmetastatic head and neck cancer.

NCT ID: NCT00978081 Completed - Clinical trials for Head and Neck Cancer

Photodynamic Therapy in Treating Patients With Premalignant or Early Stage Head and Neck Tumors

Start date: January 2009
Phase: Phase 1
Study type: Interventional

RATIONALE: Photodynamic therapy uses a drug that becomes active when it is exposed to a certain kind of light. When the drug is active, tumor cells are killed. PURPOSE: This randomized phase I trial is studying the side effects and best dose of photodynamic therapy in treating patients with premalignant or early stage head and neck tumors.