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Simplification of Complex Insulin Regimens With Preserving Good Glycemic Control in Type 2 Diabetes

Hypoglycemia Clinical Trial

Official title:
Simplification of Complex Insulin Regimens With Preserving Good Glycemic Control in Type 2 Diabetes

Clinical Trial Summary

This study examines prospectively the safety and efficacy of switching from multiple daily insulin injections (MDI) to once daily IDegLira (insulin degludec and liraglutide fix ratio combination), a fixed-ratio combination of insulin degludec and liraglutide, in relatively well controlled (HbA1c<7.5%) subjects with type 2 diabetes using low total daily insulin dose (TDD).

Clinical Trial Description

Type 2 diabetic patients suffering from severe hyperglycemia are often apply multiple daily insulin injections (MDI). If glucose toxicity resolves, the regimen may potentially be simplified, but there are no specific guidelines regarding this and a lot of patients are left on MDI. The Investigators aimed to examine prospectively the safety and efficacy of switching from MDI to once daily IDegLira, a fixed-ratio combination of insulin degludec and liraglutide, in relatively well controlled (HbA1c<7.5%) subjects with type 2 diabetes using low total daily insulin dose (TDD). The investigators hypothesize that in everyday clinical practice switching from low dose MDI to IDegLira in patients of different ages with well-controlled (or overcontrolled) type 2 diabetes is safe, may induce weight loss and result in similar or better glycemic control. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04020445
Study type Observational
Source Bekes County Central Hospital
Contact
Status Completed
Phase
Start date January 1, 2016
Completion date January 1, 2022
View Details
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