Progressive Strength in Hand Osteoarthritis

Hand Osteoarthritis Clinical Trial

Official title:

Effectiveness of a Progressive Resistance Strength Program on Hand Osteoarthritis: a Randomized Controlled Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02528630
• Other study ID #: CEP UNIFESP
• Status: Completed
• Phase: Phase 4
• First received: August 17, 2015
• Last updated: February 19, 2017
• Start date: October 2013
• Est. completion date: October 2015

Study information

• Verified date: February 2017
• Source: Federal University of São Paulo
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Background: Hand osteoarthritis (OA) is highly prevalent, affecting 55-70% of the population over 55 years with an age-related progressive increase. The OA of interphalangeal (IF) and carpometacarpal joints may have varying degrees of deformity associated with pain, decreased of grip and pinch strength, decreased range of motion and functional impairment. Systematic reviews and meta-analyzes have shown the beneficial effect of exercise for lower limb OA, however for hand OA exercise is still used based on recommendations based on clinical experience and low quality studies, not allowing a conclusion about the effects of exercise in pain, function and strength in hand OA patients.

Objective: assess the effectiveness of progressive resistance strength training program on pain, function and strength in hand OA patients.

Methods: diagnostic of hand OA according to American College of Rheumatology of at least 1year, age over 50 years, both genders, pain in IF joints between 3-8 cm on a 10-cm numerical pain scale (NPS). Sixty patients who meet the eligibility criteria were randomized into exercise group (EG) and control group (CG). Both groups performed a session regarding joint protection and energy conservation before randomization. The EG performed a progressive resistance strength training program for intrinsic muscles of the hand for 12 weeks. The outcome measures were NPS; Australian/Canadian (AUSCAN) Hand Osteoarthritis Index and Cochin Hand Functional Scale for hand function; grip and pinch strengthening using the Hydraulic Hand Dynamometer and a pinch gauge dynamometer and satisfaction with the treatment using a Likert scale. A blinded evaluator performed the evaluations at baseline, 6 and 12 weeks after treatment baseline.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: October 2015
• Est. primary completion date: January 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 50 Years and older

Eligibility

Inclusion Criteria:

• diagnostic of hand OA according to american college of rheumatology of at least 1year;

• age over 50 years;

• both genders;

• pain in interphalangeal joints between 3-8 cm on a 10-cm numerical pain scale

Exclusion Criteria:

• other joint disease in hands;

• other rheumatic systemic disease;

• surgery in hands or writs;

• exercise or joint injection in hands in the previous 3 months;

• disability to perform the exercises.

Related Conditions & MeSH terms

• Hand Osteoarthritis
• Osteoarthritis

Intervention

Other:
• Progressive resistance strength training program
Patients undergo to strength training for intrinsic muscles of the hand twice a week, during 12 weeks.
• Joint protection and energy conservation advice
A session regarding joint protection and energy conservation for hands was done before randomization.

Locations

Country	Name	City	State
Brazil	Universidade Federal de Sao Paulo	Sao Paulo	SP

Sponsors (1)

Lead Sponsor	Collaborator
Federal University of São Paulo

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in Pain	Measured by a numerical pain scale	Baseline, after 6 and 12 weeks
Secondary	Change in hand function	measured by AUSCAN	Baseline, after 6 and 12 weeks
Secondary	Change in Patient satisfaction with treatment	Measured by a Likert scale	6 and 12 weeks
Secondary	Change in grip strength	Measured by a Grip Hydraulic Hand Dynamometer	Baseline, after 6 and 12 weeks
Secondary	Change in hand function	Measured by COCHIN questionnaires	Baseline, after 6 and 12 weeks
Secondary	Change in pinch stength	Measured by pinch gauge dynamometer	Baseline, after 6 and 12 weeks