Clinical Trials Logo

Clinical Trial Summary

Background: Hand osteoarthritis (OA) is highly prevalent, affecting 55-70% of the population over 55 years with an age-related progressive increase. The OA of interphalangeal (IF) and carpometacarpal joints may have varying degrees of deformity associated with pain, decreased of grip and pinch strength, decreased range of motion and functional impairment. Systematic reviews and meta-analyzes have shown the beneficial effect of exercise for lower limb OA, however for hand OA exercise is still used based on recommendations based on clinical experience and low quality studies, not allowing a conclusion about the effects of exercise in pain, function and strength in hand OA patients.

Objective: assess the effectiveness of progressive resistance strength training program on pain, function and strength in hand OA patients.

Methods: diagnostic of hand OA according to American College of Rheumatology of at least 1year, age over 50 years, both genders, pain in IF joints between 3-8 cm on a 10-cm numerical pain scale (NPS). Sixty patients who meet the eligibility criteria were randomized into exercise group (EG) and control group (CG). Both groups performed a session regarding joint protection and energy conservation before randomization. The EG performed a progressive resistance strength training program for intrinsic muscles of the hand for 12 weeks. The outcome measures were NPS; Australian/Canadian (AUSCAN) Hand Osteoarthritis Index and Cochin Hand Functional Scale for hand function; grip and pinch strengthening using the Hydraulic Hand Dynamometer and a pinch gauge dynamometer and satisfaction with the treatment using a Likert scale. A blinded evaluator performed the evaluations at baseline, 6 and 12 weeks after treatment baseline.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02528630
Study type Interventional
Source Federal University of São Paulo
Contact
Status Completed
Phase Phase 4
Start date October 2013
Completion date October 2015

See also
  Status Clinical Trial Phase
Completed NCT01910116 - Efficacy of Shinabro in Hand Osteoarthritis Phase 2/Phase 3
Completed NCT02612233 - Pain Management in Osteoarthritis Using the Centrally Acting Analgesics Duloxetine and Pregabalin Phase 4
Completed NCT01249391 - Splinting to Treat Hand Osteoarthritis Phase 2
Recruiting NCT04402047 - Electroacupuncture vs Topical Diclofenac Sodium Gel for Patients With Hand Osteoarthritis N/A
Completed NCT03911570 - Crystalline Glucosamine Sulfate Therapy in Hand Osteoarthritis
Completed NCT04576403 - Heated Mittens for Patients With Hand Osteoarthritis N/A
Completed NCT01874067 - C-GLOVES: the Effectiveness of Compression Gloves in Arthritis
Suspended NCT03703934 - Central Pain Mechanisms in Patients With Hand-Osteoarthritis, Psoriatic Arthritis and Healthy Controls
Completed NCT04585113 - Diagnostic Accuracy of Dual-energy CT
Completed NCT05568875 - Happy Hands - an E-self-management Intervention for People With Hand Osteoarthritis N/A
Completed NCT03693833 - CBD Treatment in Hand Osteoarthritis and Psoriatic Arthritis. Phase 2
Completed NCT05150171 - Happy Hands E-self-management Pilot Study N/A
Completed NCT02667145 - Assistive Device for Hand Osteoarthritis N/A
Completed NCT02477059 - Effect of the Interleukin-6 Receptor Antagonist Tocilizumab in Patients With Hand Osteoarthritis Phase 3
Recruiting NCT04611347 - Topical CBD in Joint Arthritis Phase 2
Completed NCT04036929 - Can we Use Estrogen-containing Therapy to Improve Pain in Women After Menopause With Hand Osteoarthritis? N/A
Completed NCT03919279 - Treatment of Erosive Digital Osteoarthritis by Transcutaneous Auricular Nerve Stimulation N/A
Recruiting NCT06329219 - Water-filtered Infrared-A Radiation in Patients With Hand Osteoarthritis N/A
Not yet recruiting NCT05216757 - Efficacy and Safety of Iguratimod in Patients With Hand Osteoarthritis (ESIGO) Phase 2/Phase 3
Completed NCT02771860 - RANKL-blockade for the Treatment of Erosive Osteoarthritis (OA) of Interphalangeal Finger Joints Phase 2