Clinical Trials Logo

Clinical Trial Summary

This is a prospective study of the safety and efficacy of nivolumab for the treatment of relapsed or residual haematological malignancies after allogeneic stem cell transplantation (alloSCT). Eligible patients will receive nivolumab at a dose of 3mg/kg intravenously every 2 weeks. The primary objective is to evaluate the incidence, severity and treatment responsiveness of GVHD following nivolumab treatment post-alloSCT.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03146468
Study type Interventional
Source Melbourne Health
Contact
Status Active, not recruiting
Phase Phase 2
Start date May 8, 2017
Completion date March 1, 2022

See also
  Status Clinical Trial Phase
Terminated NCT03978312 - Nutrition Health Literacy of Cancer Patients and Their Support Networks.
Recruiting NCT03750994 - Economic Evaluation of Innovative Molecular Analyses in Onco-haematology
Recruiting NCT04397705 - Remote Monitoring of Cancer Patients With Suspected Covid-19 Phase 1
Recruiting NCT05678621 - Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or Extension Phase 2/Phase 3
Recruiting NCT05203809 - Continuous Temperature Monitoring for tHe Early Recognition of Febrile Neutropenia in Haematological MALignancies
Recruiting NCT05298930 - Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Transplantation N/A
Not yet recruiting NCT06395220 - Kinectics of Donor-specific Anti-HLA Antibody After HLA-incompatible Allogeneic Haematopoietic Stem Cell Transplantation
Recruiting NCT05786716 - DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Teenage/Young Adult and Paediatric Patients With Cancers With HER2 Amplification or Activating Mutations Phase 2/Phase 3
Not yet recruiting NCT04673305 - Cognitive Status Assessment In Elderly Patients With Active Treatment For Haematological Malignancies N/A
Recruiting NCT05768178 - DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers. Phase 2/Phase 3
Recruiting NCT05722886 - DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol Phase 2/Phase 3
Completed NCT03855969 - Central Venous Access Device Removal in Cancer Patients
Recruiting NCT04174053 - Concordance Between 2 Means of Temperature Measure in Neutropenic Patients Hospitalized in Intensive Hematology Care Units N/A
Recruiting NCT05770544 - DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Teenage/Young Adults and Paediatric Patients With ROS1 Gene Fusion-positive Cancers. Phase 2/Phase 3
Recruiting NCT05379738 - Impact of Adapted Physical Activity on Patient's Recovery Following Allogeneic Stem Cell Transplantation for Hematological Malignancy N/A
Completed NCT04236063 - Rehabilitation Needs of the Malaysian Haematological Cancer Survivors
Recruiting NCT05695638 - Proseq Cancer: Genomic Profiling in Patients With Incurable Cancer in Search for Targeted Treatment
Recruiting NCT04298892 - Integrated Multiomics and Multilevel Characterization of Haematological Disorders and Malignancies
Withdrawn NCT03688789 - Hématologie Adulte Prevalence of Adrenal Insufficiency Post-chemotherapy Adrenocorticotropia in Adult Hematology N/A
Withdrawn NCT04331483 - A Study to Assess a Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Allografts N/A