Screening of Helicobacter Pylori in Children of Positive Infected Mothers

H Pylori Infection Clinical Trial

Official title:

Screening of Helicobacter Pylori Infection in Children of Positive Infected Mothers

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03911791
• Other study ID #: Prevelance of H Pylori
• Status: Not yet recruiting
• Start date: April 1, 2020
• Est. completion date: April 1, 2021

Study information

• Verified date: March 2019
• Source: Assiut University
• Contact: Mohamed Professor Hamdy, Professor
• Phone: 01001296603
• Email: Mohamed.ghazali1[@]med.au.edu.eg
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Helicobacter pylori is aspiral shaped gram negative organism that colonized the gastric mucosa.it was showen that intra familial infection play role in transmission of H pylori and mother play the key role in transmission .

Description:

Prevelance of H pylori infection in children whose mother positive infected is different according to risks factors such as mother education,work out side or not , socioeconomic status, family size and breast feeding or not.H pylori in children can be represent with recurrent abdominal pain ,recurrent diarrhea,repeated vomitting ,pallor ,fulness,non variceal hematemesis,loss of appetite,reterded growth.complication of H pylori include gastric ulcer,duodenal ulcer,gastric atrophy may lead to gastric cancer and intestinal metaplasia.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 30
• Est. completion date: April 1, 2021
• Est. primary completion date: April 1, 2020
• Gender: All
• Age group: N/A to 13 Years

Eligibility

Inclusion Criteria:

Child with Dyspeptic symptoms

Exclusion Criteria:

malnutrition childs Patient with metabolic disorder

Related Conditions & MeSH terms

• H Pylori Infection
• Infection

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (2)

Greenberg ER, Chey WD. Defining the role of sequential therapy for H pylori infection. Lancet. 2013 Jan 19;381(9862):180-2. doi: 10.1016/S0140-6736(12)61849-2. Epub 2012 Nov 16. — View Citation

Warren JR, Marshall B. Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet. 1983 Jun 4;1(8336):1273-5. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	To assess prevelance of H pylori infection in children born of infected positive mother	By taken children whose mother infected ,how many of them infected by this microbe by taken these child and done the following investigastion as stool antigen test and biobsy if they are postive by test and then follow up by treatment	Period from April 2019 to April 2020
Primary	Asse the effect of Helicobacter pylori infection in children with anemia	By knowing effect of this microbe on growth development of children by measure weigt /height through body mass index and measure heamoglbin level; By taken children whose positive H pylori follow effect of this microbe on heamoglbin level and do investigation as complete blood count By following test such as complete blood count and heamoglbin level and if this microbe increase level of anemia or not	Period from April 2019 to April 2020