Firm Observational Clinical Unicenter Study on Guillain Barré Syndrome

Guillain-Barre Syndrome (GBS) Clinical Trial

— FOCUS on GBS  

Official title:

Firm Observational Clinical Unicenter Study on Guillain Barré Syndrome (FOCUS on GBS)

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04829526
• Other study ID #: 2021-00402; ko21Sutter
• Status: Recruiting
• Start date: March 1, 2021
• Est. completion date: December 2022

Study information

• Verified date: May 2022
• Source: University Hospital, Basel, Switzerland
• Contact: Raoul Sutter, Prof. Dr. med.
• Phone: +41 61 32 87 928
• Email: raoul.sutter[@]usb.ch
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of this retrospective observational single-center cohort study is to gain a deeper understanding regarding the frequency, the clinical and electrophysiologic characteristics (e.g., the diagnostic work up), complications, treatment regimes, and their associations with specific courses of disease and outcomes in adult patients with the suspected or proven diagnosis of GBS.

Description:

Guillain Barré Syndrome (GBS) is a rare and life-threatening neurological emergency. The aim of this retrospective study including adult GBS patients from the last 15 years treated at the University Hospital of Basel is to assess data regarding diagnostic workup, treatment, clinical course including complications and outcomes.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: December 2022
• Est. primary completion date: December 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• suspected diagnosis of GBS, who have been treated at the University Hospital of Basel from 01.01.2005-28.02.2021

Exclusion Criteria:

• Patients with documented refusal of the general consent.

Related Conditions & MeSH terms

• Guillain-Barre Syndrome
• Guillain-Barre Syndrome (GBS)
• Syndrome

Intervention

Other:
• data collection
Retrospective extraction of demographic, clinical, laboratory, and electrophysiological data from the digital medical records

Locations

Country	Name	City	State
Switzerland	Clinic for Intensive Care Medicine; University Hospital Basel	Basel

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Basel, Switzerland

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	frequency of GBS	frequency of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)	one time retrospective assessment at baseline
Primary	clinical characteristics of GBS	clinical characteristics of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)	one time retrospective assessment at baseline
Primary	electrophysiologic characteristics of GBS	electrophysiologic characteristics of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)	one time retrospective assessment at baseline
Primary	complications of GBS	complications of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)	one time retrospective assessment at baseline
Primary	treatment regimes of GBS	treatment regimes of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)	one time retrospective assessment at baseline
Primary	outcomes of GBS	treatment regimes of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel)	one time retrospective assessment at baseline