Granuloma Annulare Clinical Trial
Official title:
Granuloma Annulare Treated With Rifampin, Ofloxacin, and Minocycline Combination Therapy
NCT number | NCT00720980 |
Other study ID # | IRB5074 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | May 2008 |
Est. completion date | July 2008 |
Verified date | April 2024 |
Source | Henry Ford Health System |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Granuloma annulare is a benign, usually self-limiting, cutaneous dermatosis, which typically presents as asymptomatic, flesh-colored or red papules, frequently arranged in an annular pattern on the distal extremities. Although localized granuloma annulare is most commonly observed, a generalized or disseminated form can occur. The etiology of granuloma annulare is unknown, however, multiple inciting factors have been proposed. The purpose of the investigators is to review the outcomes of treatment of granuloma annulare (GA) resistant to standard regimens that resolved after a 3-months treatment course of monthly rifampin, ofloxacin, and minocycline (ROM) therapy, successfully used to treat paucibacillary leprosy, a disease with clinical and histopathologic similarity to GA.
Status | Completed |
Enrollment | 6 |
Est. completion date | July 2008 |
Est. primary completion date | May 2008 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: - Patients with granuloma annulare who are resistent to the standard treatment. Exclusion Criteria: - Response to the standard treatment of granuloma annulare. |
Country | Name | City | State |
---|---|---|---|
United States | Henry Ford Medical Center | Detroit | Michigan |
Lead Sponsor | Collaborator |
---|---|
Henry Ford Health System |
United States,
Duarte AF, Mota A, Pereira MA, Baudrier T, Azevedo F. Generalized granuloma annulare--response to doxycycline. J Eur Acad Dermatol Venereol. 2009 Jan;23(1):84-5. doi: 10.1111/j.1468-3083.2008.02707.x. Epub 2008 Apr 1. No abstract available. — View Citation
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