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Study of MEDI 507 in the Treatment of Pediatric Patients — Pediatric GvHD  

Graft Versus Host Disease Clinical Trial

Official title:
Phase I Study of MEDI 507 in the Treatment of Pediatric Patients With at Least Grade II Acute Graft-Versus-Host Disease (GvHD)

Clinical Trial Summary

To assess the safety of escalating dose levels of MEDI-507 in pediatric stem cell and bone marrow allograft recipients who have at least Grade II GvHD.

Clinical Trial Description

This is a Phase I, open-label dose escalation trial of MEDI-507 in pediatric SCT and BMT recipients with at least Grade II acute GvHD. All patients will receive steroid therapy and MEDI-507 for treatment of GvHD ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00813618
Study type Interventional
Source MedImmune LLC
Contact
Status Completed
Phase Phase 1
Start date September 1999
Completion date August 2004
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