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The Role of Oxytocin in Regulating Blood Glucose — GLOXY-1  

Glucose Metabolism Disorders (Including Diabetes Mellitus) Clinical Trial

Official title:
The Role of Oxytocin in Regulating Blood Glucose

Clinical Trial Summary

Investigating the effect of oxytocin on pancreatic endocrine functions by determining insulin and glucagon secretion within physiological ranges of plasma glucose.

Clinical Trial Description

Insulinotropic effects of oxytocin will be examined in 20 healthy men with body mass index (BMI) < 27 kg/m2, during a graded glucose infusion test with concomitant intravenous infusion of synthetic oxytocin or placebo in a randomized, double-blinded design. This will determine the effect of oxytocin on glucose-stimulated insulin and glucagon secretion. Additional changes in plasma/serum concentrations of C-peptide, glucose, glucose-dependent insulinotropic polypeptid (GIP), glucagon-like peptide 1 (GLP-1), and lipids will be assessed. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06334172
Study type Interventional
Source University Hospital, Gentofte, Copenhagen
Contact Vivian Kliim-Hansen, MD
Phone +4524476875
Email vivian.kliim-hansen@regionh.dk
Status Recruiting
Phase N/A
Start date January 1, 2024
Completion date December 31, 2026
View Details
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