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Glucocorticoid clinical trials

View clinical trials related to Glucocorticoid.

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NCT ID: NCT05329740 Completed - Aortic Dissection Clinical Trials

Glucocorticoids for Post-operative Patients With Acute Type A Aortic Dissection (The GLAD Trial)

Start date: February 7, 2022
Phase: Phase 4
Study type: Interventional

This study is designed to evaluate the effects of glucocorticoid(GC) on improving post-operative organ dysfunction in patients with acute type A aortic dissection(aTAAD). Subjects with confirmed diagnosis of aTAAD undergoing surgical treatment will be enrolled and 1:1 randomly assigned to receive either glucocorticoids or normal treatment. All patients in the glucocorticoids group will be given methylprednisolone intravenously for 3 days after enrollment. The primary endpoint will be the amplitude of variation of Sequential Organ Failure Assessment score on post-operative day 4 compared to baseline.

NCT ID: NCT03525028 Recruiting - Uveitis Clinical Trials

A Clinical Trial of Metformin to Decrease Glucocorticoids Side Effects in Patients With Autoimmune Uveitis

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

This project is designed to evaluating the use of combination therapy of glucocorticoid and metformin to decrease glucocorticoid side effects in participants with autoimmune uveitis.This study also aims to evaluate the anti-inflammatory and immunosuppressive effects of combination therapy.

NCT ID: NCT02872584 Not yet recruiting - Glucocorticoid Clinical Trials

Serum FFA Desaturase Activity Index in Patients on High Dose Corticosteroids

FFA&steroids
Start date: September 2016
Phase: N/A
Study type: Observational

Free fatty acid index will be measured in patients before and 1 month after high dose prednisone.

NCT ID: NCT01294319 Completed - ACTH Clinical Trials

Evaluation of Cortisol Resistance in Young Sedentary and Endurance-Trained Men

Start date: January 24, 2011
Phase: Phase 2
Study type: Interventional

This study proposes to examine multiple aspects of the hypothalamic-pituitary-adrenal axis in younger endurance trained and sedentary men, and in older sedentary men.