Glioma Clinical Trial
— DT-MiNiOfficial title:
Presence of Microplastics and Nanoplastics in Neurosurgery Patients
Plastic particles are a ubiquitous pollutant in the living environment and food chain, so far, plenty of studies have reported the internal exposure of microplastics and nanoplastics in human tissues and enclosed body fluids. Neurosurgery is the only department that can open the skull. In addition to blood and cerebrospinal fluid, there are brain tissue and tumors in the presence of lesions. Whether any of these microplastics and nanoplastics are present remains a mystery. This prospective observational study will harvest biological samples of neurosurgery patients. The objective of this research is to be able to detect microplastics and nanoplastics on blood and operation samples of neurosurgery patients.
| Status | Recruiting |
| Enrollment | 500 |
| Est. completion date | December 31, 2025 |
| Est. primary completion date | December 31, 2025 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years to 80 Years |
| Eligibility | Inclusion Criteria: - Age 18-80 years - Any type of neurosurgery Exclusion Criteria: ·refusal of the patient to participate |
| Country | Name | City | State |
|---|---|---|---|
| China | Beijing Tiantan Hospital, Capital Medical University | Beijing | Beijing |
| Lead Sponsor | Collaborator |
|---|---|
| Beijing Tiantan Hospital |
China,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | microplastics | Detection of microplastics in human brain tissue and the blood undergoing neurosurgery | baseline, intraoperative | |
| Primary | nanoplastics | Detection of nanoplastics in human brain tissue and the blood undergoing neurosurgery | baseline, intraoperative |
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