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Clinical Trial Summary

The most aggressive primary brain tumors in adults, glioblastomas, are characterized by a profound local and systemic immune suppression. During tumor progression, the infiltration of inflammatory leukocytes, especially of myeloid origin, endowed with immunosuppressive function is observed. Aim of this study is to evaluate myeloid cell infiltrate and iron metabolism in tumor-associated macrophages by combining a multimodal MRI imaging technique with immunophenotyping of the tumor microenvironment.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05267509
Study type Observational
Source Istituto Oncologico Veneto IRCCS
Contact Susanna Mandruzzato, PhD
Phone +39 049 8215898
Email susanna.mandruzzato@unipd.it
Status Recruiting
Phase
Start date February 23, 2022
Completion date January 31, 2025

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