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Clinical Trial Summary

This study aims to evaluate the safety and effectiveness of the combination of 30Gy/5fx HSRT and 20Gy/10fx IMRT adjuvant therapy. The total biological effective dose (BED) of the PTV is 72 Gy in a ratio of alpha/beta ratio of 3, which equals to the conventional 60Gy/30fx treatment. This study can provide evidence for future non-inferiority phase III randomized controlled trials. The abbreviated course of radiotherapy can reduce the treatment time by half, benefit patients, and utilize the health resource.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04547621
Study type Interventional
Source Huashan Hospital
Contact
Status Active, not recruiting
Phase Phase 1/Phase 2
Start date September 1, 2020
Completion date January 1, 2024

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