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Clinical Trial Summary

This study aims to evaluate the safety and effectiveness of the combination of 30Gy/5fx HSRT and 20Gy/10fx IMRT adjuvant therapy. The total biological effective dose (BED) of the PTV is 72 Gy in a ratio of alpha/beta ratio of 3, which equals to the conventional 60Gy/30fx treatment. This study can provide evidence for future non-inferiority phase III randomized controlled trials. The abbreviated course of radiotherapy can reduce the treatment time by half, benefit patients, and utilize the health resource.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT04547621
Study type Interventional
Source Huashan Hospital
Status Active, not recruiting
Phase Phase 1/Phase 2
Start date September 1, 2020
Completion date January 1, 2024

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