The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters.

Glaucoma Clinical Trial

Official title:

The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters.

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT06340061
• Other study ID #: Qianyu Wu
• Status: Active, not recruiting
• Start date: October 20, 2022
• Est. completion date: December 31, 2024

Study information

• Verified date: March 2024
• Source: Henan Provincial People's Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared. Additionally, an investigation was conducted to explore the relationship between anterior chamber parameters, corneal biomechanics, and the severity of glaucoma

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 80
• Est. completion date: December 31, 2024
• Est. primary completion date: December 31, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 22 Years to 79 Years

Eligibility

Inclusion Criteria:

• Clinical diagnosis of primary glaucoma.
• Must be able to cooperate to complete the inspection.

Exclusion Criteria:

• Secondary glaucoma.
• Corneal disease (E. g., keratitis, corneal scarring) that the investigator believes may affect the examination.
• trauma
• congenital eye malformations

Related Conditions & MeSH terms

• Glaucoma

Intervention

Other:
• Observational study
The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared. Additionally, an investigation was conducted to explore the relationship between anterior chamber parameters, corneal biomechanics, and the severity of glaucoma

Locations

Country	Name	City	State
China	Henan Provincial People's Hospital	Zhengzhou	Henan

Sponsors (1)

Lead Sponsor	Collaborator
Henan Provincial People's Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	IOP	Intraocular pressure	through study completion, an average of 2 years.
Primary	bIOP	Biomechanical intraocular pressure. Corneal Biomechanics Parameters.	through study completion, an average of 2 years.
Primary	ACD	Anterior chamber depth. Anterior Chamber Parameters.	through study completion, an average of 2 years.
Primary	ACW	Anterior chamber width. Anterior Chamber Parameters.	through study completion, an average of 2 years.
Primary	SSI	Stress-strain index. Corneal Biomechanics Parameters.	through study completion, an average of 2 years.
Primary	VF	visual field. The severity of glaucoma is mainly based on the damage of the visual field	through study completion, an average of 2 years.