Study on Intraocular Structural Parameters and Surgical Effect Before and After the Onset of Malignant Glaucoma

Glaucoma Clinical Trial

— MG  

Official title:

Study on Intraocular Structural Parameters and Surgical Effect Before and After the Onset of Malignant Glaucoma

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04220879
• Other study ID #: 2019KYPJ148
• Status: Recruiting
• Start date: November 25, 2019
• Est. completion date: November 24, 2020

Study information

• Verified date: January 2020
• Source: Zhongshan Ophthalmic Center, Sun Yat-sen University
• Contact: Dingqiao O Wang, M.D
• Phone: 020-66615461
• Email: wangdingqiao[@]163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

In this retrospective observational study, we collected intraocular structure parameters of malignant glaucoma and primary angle closure glaucoma. Anterior chamber depth (ACD) and width (ACW), lens vault (LV), ciliary process-ciliary process distance(CCD), trabecular-ciliary processes distance (TCPD), ciliary body max thickness (CBMT), peripheral iris thickness (PIT), trabecular ciliary process angle (TCPA), and anterior vault (AV), were measured by ultrasound biomicroscopy. Other parameters measured by A-scan ultrasonography and optical coherence tomography. To analyze the high risk factors and the possible pathogenesis of the disease and discuss the long-term effect of different treatment methods.

Description:

Outcome Measures:

Anterior chamber depth (ACD) and width (ACW), lens vault (LV), ciliary process-ciliary process distance(CCD), trabecular-ciliary processes distance (TCPD), ciliary body max thickness (CBMT), peripheral iris thickness (PIT), trabecular ciliary process angle (TCPA), and anterior vault (AV), were measured by ultrasound biomicroscopy. Other parameters measured by A-scan ultrasonography and optical coherence tomography.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: November 24, 2020
• Est. primary completion date: August 24, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria: (1) history of operation, (2) diagnosis of MG, and (3) eyes with clear optical media.

Exclusion Criteria:(1)hypertension or diabetes and (2) diagnosis of ocular fundus diseases.

Related Conditions & MeSH terms

• Glaucoma
• Malignant Glaucoma

Locations

Country	Name	City	State
China	Zhognshan Ophthalmic Center, Sun Yat-sen University	Guangzhou	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
Zhongshan Ophthalmic Center, Sun Yat-sen University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Trabecular ciliary process angle	TCPA is measured with its apex at the scleral spur, one arm along the posterior corneal surface, and another arm along the most anterior surface of the ciliary body	baseline
Primary	Choroidal vascularity parameter	Choroidal vascularity parameter is a vessel ratio measured by optical coherence tomographic images	baseline