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The Asia Primary Tube Versus Trab (TVT) Study — TVT  

Glaucoma Clinical Trial

Official title:
The Asia Primary Tube Versus Trab (TVT) Study

Clinical Trial Summary

Comparison of Ahmed Glaucoma Implant (AGI) against trabeculectomy with mitomycin C in patients with uncontrolled open angle glaucoma

Clinical Trial Description

The objective of the Asia Primary Tube versus Trab (TVT) study is to compare the efficacy and safety of placement of an Ahmed Glaucoma Implant (AGI) (New World Medical Inc., Rancho Cucamonga, CA, USA) against trabeculectomy with mitomycin C in patients with uncontrolled glaucoma, who may or may not have had previous clear corneal cataract surgery with intraocular lens implantation, over 5 years. Outcome discrimination between the two treatment groups will be made using following parameters:

1. Intraocular pressure

2. Need for supplemental medical therapy

3. Incidence of short and long term surgical complications and need for re-operation.

4. Visual function (Visual acuity and Visual field)

Hypothesis: Glaucoma drainage implants have better surgical outcomes in terms of IOP lowering efficacy compared to trabeculectomy with mitomycin-C over 5 years in Asian patients with medically uncontrolled glaucoma. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03274024
Study type Interventional
Source Singapore Eye Research Institute
Contact Natalia Porporato, Fellow
Phone +6591378217
Email natalia.porporato@gmail.com
Status Recruiting
Phase N/A
Start date September 28, 2016
Completion date October 30, 2020
View Details
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