Evaluation of Corneal Temperature by Infrared Thermography in Glaucoma Patients

Glaucoma Clinical Trial

Official title:

Evaluation of Corneal Temperature by Infrared Thermography in Glaucoma Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02674074
• Other study ID #: EKNZ 120/11
• Status: Completed
• Phase: N/A
• First received: January 27, 2016
• Last updated: February 25, 2016
• Start date: June 2011
• Est. completion date: September 2013

Study information

• Verified date: February 2016
• Source: University Hospital, Basel, Switzerland
• Contact: n/a
• Is FDA regulated: No
• Health authority: Switzerland: Cantonal Office of Public Health
• Study type: Interventional

Clinical Trial Summary

Measurement of corneal temperature gives indirect information about the ocular blood flow. For this reason corneal temperature can be used as a surrogate to quantify ocular blood flow. It can be measured by means of infrared thermography. This test, however, is not used in an everyday clinical routine so far. In this study is investigated if ocular blood flow disturbances in glaucoma patients can be diagnosed by means of infrared thermography.

Corneal temperature are measured in normal tension glaucoma patients and healthy controls before and after cold provocation test. In the group of patients and the group of controls, subjects with and without a primary vascular dysregulation (PVD) are included. This will allow to analyze and compare the influence of cold provocation on corneal temperature (and indirectly ocular blood flow) in these study Groups.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: September 2013
• Est. primary completion date: September 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria for Patients:

• Glaucoma

• Age 18-65

Exclusion Criteria for patients:

• No Glaucoma

• Alcohol consumption

• Smoking

Inclusion Criteria for Control:

• No Glaucoma

• Age 18-65

Exclusion Criteria for control:

• Alcohol consumption

• Smoking

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Glaucoma

Intervention

Device:
• infrared thermography
measurement of corneal temperature by infrared thermography before and after cold provocation

Locations

Country	Name	City	State
Switzerland	Department of Ophthalmology, University Hospital Basel	Basel

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Basel, Switzerland

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Corneal temperature measurement by infrared thermography	measurement of change in corneal temperature starting with first measurement at Baseline and second measurement after 5 minutes	2 measurements with interval of 5 minutes starting at baseline	No