Glaucoma Clinical Trial
Official title:
RAPDx Pupillography for Early Detection of Glaucoma
The Konan RAPDx (Konan Medical USA, Irvine, CA) is a newly patented pupillography device.The aims of this study are to assess the ability of the RAPDx to distinguish between healthy subjects and patients with confirmed glaucoma using standard testing sequences developed for use at the Wills Eye Hospital Glaucoma Research Center and to determine the combination of demographic, clinical, and RAPDx testing parameters which allow for maximum sensitivity and specificity.
The RAPDx utilizes noninvasive digital, high-definition, infrared machine-vision with
eye-tracking and automated blink detection technology to analyze and quantify the pupillary
response to light.
During the scheduled appointment, all patients will receive an undilated fundus examination
by the attending ophthalmologist. The following data will be collected; Demographic
information, Visual acuity, Intraocular pressure (IOP) measured by Goldmann applanation
tonometry, Disc damage likelihood scale (DDLS), Vertical cup/disc ratio, Gonioscopy (if not
documented in the chart within the past 2 years) and Humphrey visual field examination.
Each participant will undergo RAPDx testing with two different testing sequences. They are
separated by a 10-second resting period during which the patient is instructed to close his
or her eyes. The exam may be paused at any time and re-alignment may be performed during any
pause. The two testing sequences are:
1. Standard Factory Setting: 0.1-second stimuli with 2-second inter-stimuli pauses;
2. Custom Setting: 3-second stimuli with 1-second inter-stimuli pauses
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