Posterior Cornea in Primary Open Angle Glaucoma

Glaucoma Clinical Trial

Official title:

Posterior Cornea in Primary Open Angle Glaucoma

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02356094
• Other study ID #: CHBaixoVouga2
• Status: Recruiting
• Phase: N/A
• First received: February 1, 2015
• Last updated: February 1, 2015
• Start date: January 2015
• Est. completion date: April 2015

Study information

• Verified date: February 2015
• Source: Centro Hospitalar do Baixo Vouga
• Contact: Pedro Gil, MSc, MD
• Phone: 00351915687941
• Email: pedroqgil[@]gmail.com
• Is FDA regulated: No
• Health authority: Portugal: Ethics Committee for Clinical Research
• Study type: Observational

Clinical Trial Summary

Characterization of posterior corneal changes in primary open angle glaucoma patients, using Scheimpflug examination.

Description:

A cohort of primary open angle glaucoma (POAG) patients is submitted to Scheimpflug Pentacam examination. The results are compared with a control group of age and central corneal thickness matched healthy subjects

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: April 2015
• Est. primary completion date: April 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Primary open angle glaucoma, with the diagnosis supported on structural and functional complementary exams according to the current European Glaucoma Society guidelines

• Healthy subjects from the General Ophthalmology Outpatient Clinic

Exclusion Criteria:

• age inferior to 18 years old

• primary closed angle glaucoma

• secondary open angle glaucoma

• previous intra-ocular surgery

• known or suspected corneal disease

• previous intra-ocular inflammation

• previous ocular trauma

Study Design

Observational Model: Case Control, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Glaucoma
• Glaucoma, Open-Angle

Intervention

Procedure:
• Pentacam
Corneal topography using Scheimpflug Pentacam examination

Locations

Country	Name	City	State
Portugal	Centro Hospitalar Baixo Vouga	Aveiro

Sponsors (1)

Lead Sponsor	Collaborator
Centro Hospitalar do Baixo Vouga

Country where clinical trial is conducted

Portugal, 

References & Publications (1)

Arranz-Marquez E, Bolivar G, Piñero DP, Konstas AG, Mikropoulos DG, Teus MA. Orbscan topography in primary open-angle glaucoma. Optom Vis Sci. 2013 Oct;90(10):1098-103. doi: 10.1097/OPX.0000000000000019. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mean posterior corneal elevation	Mean posterior corneal elevation based on the relative elevation of the cornea related with the best-fit sphere	Single point in time, at baseline at the moment of study enrollment	No
Secondary	Mean anterior corneal elevation	Mean anterior corneal elevation based on the relative elevation of the cornea related with the best-fit sphere	Single point in time, at baseline at the moment of study enrollment	No