Glaucoma Clinical Trial
Official title:
Comparing Diurnal Fluctuations in Intra Ocular Pressure Measured in Same Day Versus Different Days in Glaucoma Patients
Glaucoma is one of the leading causes of blindness in the west. The disease caused by high
intra ocular pressure (IOP) and characterized by damage to the optic nerve and gradual loss
of visual field. Intra ocular pressure change during the day. To evaluate the efficiency of
the therapy it is common to measure the intra ocular pressure at different times of the day.
Most ophthalmologists admit the patient for one day at which intra ocular pressure is
measured at different times. This method does not mimic the patient daily routine and may
not reflect the true diurnal fluctuations.
For this reason some ophthalmologists measure the intra ocular pressure at different times
and at different days. It is not known if both methods give similar diurnal curves.
A study physician will install anesthetic eye drops and will color the eye drops film with
fluorescein. Study physician will use tonometer to measure the intra ocular pressure in each
eye. This is a standard procedure done in any ophthalmological examination. Each patient
will undergo intraocular pressure examination at 8:00, 12:00 and 16:00.
In the first day intra ocular pressure will be measured at 8:00, 12:00 and 16:00, same day
measurements. The day after intra ocular pressure will be measured at 8:00, two days after
at 12:00 and three days after at 16:00. One month later the patient will undergo another
serious of intra ocular pressure measurements.
In the first day intra ocular pressure will be measured at 8:00, 12:00 and 16:00, same day
measurements. The day after intra ocular pressure will be measured at 8:00, two days after
at 12:00 and three days after at 16:00.
The relationship between the two diurnal curves will be analyzed.
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Observational Model: Case-Only, Time Perspective: Prospective
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