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NCT00804063 Clinical Trial

Serum Citrate in Diagnosis and Follow-up for Glaucoma

Glaucoma Clinical Trial

Official title:
Serum Citrate in Diagnosis and Follow-up for Glaucoma

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00804063
Other study ID # EK 325/08
Secondary ID
Status Completed
Phase N/A
First received December 5, 2008
Last updated January 7, 2015
Start date December 2008
Est. completion date July 2013

Study information
Verified date January 2015
Source University Hospital, Basel, Switzerland
Contact n/a
Is FDA regulated No
Health authority Switzerland: EthikkommissionSwitzerland: Laws and standards
Study type Observational

Clinical Trial Summary

Glaucoma might be a mitochondria associated disease. Since citrate is a major component in mitochondrial metabolism its determination in blood might serve as a biomarker.

Recruitment information / eligibility
Status Completed
Enrollment 20
Est. completion date July 2013
Est. primary completion date December 2012
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- age> 18 years

- glaucoma

Exclusion Criteria:

- Active ocular inflammation

- Ocular Hypertension

- Nephropathy

- Alcohol-, Drug abuse

- Mitochondriopathy

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Intervention

Procedure:
• drawing blood sample
fasting blood sample

Locations
Country Name City State
Switzerland University Hospital Basel Basel Basel-Stadt

Sponsors (2)
Lead Sponsor Collaborator
University Hospital, Basel, Switzerland Kantonsspital Baselland Bruderholz

Country where clinical trial is conducted

Switzerland, 

Outcome
Type Measure Description Time frame Safety issue
Primary serum citrate level 1 No
Secondary urine citrate 1 No
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