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NCT00788762 Clinical Trial

Myocilin Variations and Familial Glaucoma in Taxiarchis

Glaucoma Clinical Trial

— Taxiarchis  

Official title:
Myocilin Variations and Familial Glaucoma in Taxiarchis, A Small Greek Village.

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT00788762
Other study ID # A6798
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date August 2007
Est. completion date December 2022

Study information
Verified date December 2020
Source Aristotle University Of Thessaloniki
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Taxiarchis, a small village in Northern Greece with 1060 inhabitants, was considered to have a surprisingly high incidence of glaucoma. This isolated population located on Mount Holomondas appeared to be enriched for familial glaucoma. Based upon the high reported incidence of glaucoma in Taxiarchis and previous findings of the Thr377Met myocilin mutation in the Greek population,the investigators undertook a community-based study to determine if this variant was present in this village.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 840
Est. completion date December 2022
Est. primary completion date December 2022
Accepts healthy volunteers No
Gender All
Age group 1 Year to 90 Years
Eligibility Inclusion Criteria: - Individuals born in Taxiarchis Exclusion Criteria: - Individuals that have not been born in Taxiarchis

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Greece Taxiarchis village Polygyros Halkidiki

Sponsors (1)
Lead Sponsor Collaborator
Aristotle University Of Thessaloniki

Country where clinical trial is conducted

Greece, 

Outcome
Type Measure Description Time frame Safety issue
Primary Examining all of the villagers to determine the actual incidence of glaucoma in Taxiarchis and identify the Thr377Met myocilin mutation in glaucoma patients. 4 years
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