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NCT00554411 Clinical Trial

Assessing Ocular Surface Changes After Changing Glaucoma Medications

Glaucoma Clinical Trial

Official title:
Assessing Changes at the Ocular Surface Following the Switch From Xalatan to Travatan Z.

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00554411
Other study ID # 07-0757
Secondary ID
Status Completed
Phase N/A
First received November 2, 2007
Last updated January 26, 2017
Start date November 2007
Est. completion date August 2011

Study information
Verified date January 2017
Source University of Colorado, Denver
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Hypothesis: Changing to Travatan Z therapy increases the tear film break up time of subjects on Xalatan therapy presenting with ocular surface disease.

Description:

Patients who have been taking Xalatan monotherapy to treat their glaucoma and presenting with ocular surface disease will be advised to switch their medication to Travatan Z. Test results will be recorded at the day that the medication was changed and at follow-up to determine if there is a measurable change in tear film break up, corneal staining and in the Ocular Surface Disease Index.

Recruitment information / eligibility
Status Completed
Enrollment 22
Est. completion date August 2011
Est. primary completion date August 2011
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- on Xalatan monotherapy from 1 to 18 months

- 18 years of age or older

- has been diagnosed with ocular surface disease

Exclusion Criteria:

- special populations such as children, pregnant females, prisoners, etc.

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States Rocky Mountain Lions Eye Institute Aurora Colorado

Sponsors (1)
Lead Sponsor Collaborator
University of Colorado, Denver

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Change in Signs and Symptoms of Ocular Surface Disease 6 months
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