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Glaucoma; Drugs clinical trials

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NCT ID: NCT06369077 Recruiting - Clinical trials for Glaucoma, Open-Angle

How Much Does Reduced Dosing of Latanoprost and Dorzolamide-timolol Affect Pressure?

Start date: April 2024
Phase: Phase 4
Study type: Interventional

IOP effect of half-dose latanoprost dorzolamide-timolol will be compared to full dose. Further comparison will be made timolol-brimonidine-dorzolamide-bimatoprost. Dry eye effects of the different treatments will be assessed.

NCT ID: NCT05319470 Completed - Glaucoma Clinical Trials

Ocular Surface Disease and IOP Monitoring With Travoprost Without Conservatives

Start date: March 15, 2022
Phase:
Study type: Observational [Patient Registry]

Primary objective of this study is to study the efficacy of travoprost without preservatives in the treatment of glaucoma patients and to monitor the ocular surface.

NCT ID: NCT04381611 Enrolling by invitation - Surgery Clinical Trials

INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register

Start date: January 15, 2019
Phase:
Study type: Observational [Patient Registry]

The study is an observational analysis of patients' medical data recorded in a large-scale register, both retrospective (for patients operated and data recorded before 2018) and prospective (for data collected after 2018) in nature.Patients' medical data contained in the register will be analysed to determine the efficacy of the treatments they received during their follow-up at the investigation centre.

NCT ID: NCT04178863 Recruiting - Glaucoma; Drugs Clinical Trials

CATS Tonometer IOP Reduction Latanoprost Verses Timolol

Start date: July 1, 2018
Phase: Phase 4
Study type: Interventional

Topical Prostaglandin Analog vs Betablocker - Corneal Biomechanical Evaluation using CATS Tonometer Prism

NCT ID: NCT04007276 Not yet recruiting - Glaucoma Clinical Trials

The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients

Start date: November 10, 2025
Phase: Phase 4
Study type: Interventional

Glaucoma represents a group of conditions that cause damage to the optic nerve and can lead to irreversible vision loss. Current treatments are aimed at lowering intraocular pressure while minimizing medication side effects. Lumify™ (Brimonidine Tartrate Ophthalmic Solution 0.025%) is an FDA-approved medication for alleviating eye redness, a common side effect of glaucoma medications. The purpose of this study is to evaluate the effect of Lumify™ on eye redness, intraocular pressure, and eyelid position in patients with glaucoma who are already using the Brimonidine 0.1%, 0.15% or 0.2% eye drops.

NCT ID: NCT03595865 Not yet recruiting - Glaucoma; Drugs Clinical Trials

Efficacy of Tafluprost as an Adjunct to Medical Therapy for Residual Glaucoma After Trabeculectomy

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

A 6-month, parallel-group study of the safety and efficacy of tafluprostin for Chinese patients with posttrabeculectomy residual primary angle-closure glaucoma or posttrabeculectomy residual primary open angle glaucoma.

NCT ID: NCT03338088 Active, not recruiting - Glaucoma; Drugs Clinical Trials

Evaluation of Adherence to Clinical Treatment of Glaucoma

Start date: September 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

Evaluation of adherence to clinical treatment of glaucoma in patients of a Reference Ophthalmological Hospital in Goiânia using Morisky Adhesion scale as a validated questionary.

NCT ID: NCT03323164 Completed - Clinical trials for Primary Open-angle Glaucoma

Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study

Start date: July 10, 2017
Phase: Phase 4
Study type: Interventional

This study evaluates the possible acute changes in peripapillary blood flow after instillation of antiglaucoma medications in patients with primary open angle glaucoma (POAG), normal tension glaucoma (NTG), or ocular hypertension (OHTN) using Optical Coherence Tomography (OCT) angiography.

NCT ID: NCT03220490 Recruiting - Glaucoma Clinical Trials

Efficacy and Necessity of Time Interval Between Instillation of Two Glaucoma Eye Drops

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

According to the American Academy of Ophthalmology's Preferred Practice Pattern on Primary Open Angle Glaucoma, patients should wait five minutes between administering topical drops for intra-ocular pressure reduction. To date, no study has shown the efficacy of this waiting period. In this study, we aim to establish the clinical significance of keeping a time interval between glaucoma medications.