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Gingivitis clinical trials

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NCT ID: NCT04597073 Completed - Gingivitis Clinical Trials

Measurement of Oncostatin M, Leukemia Inhibitory Factor and Interleukin-11 Levels of Patients With Periodontal Disease

Start date: March 2014
Phase: N/A
Study type: Interventional

This study aims to determine Oncostatin M (OSM), Leukemia inhibitory factor (LIF), and Interleukin-11 (IL-11) levels in gingival crevicular fluid (GCF), saliva, and serum in periodontally healthy individuals and those with gingivitis and chronic periodontitis before and after periodontal treatment and to evaluate the relationship between these cytokine levels and clinical periodontal parameters.

NCT ID: NCT04596761 Completed - Gingivitis Clinical Trials

ToothWave Calculus Reduction and Accumulation Prevention Study

Start date: July 15, 2020
Phase: N/A
Study type: Interventional

The objective of the study is to evaluate the safety and efficacy of the home-use device ToothWave (Model H7001) for calculus reduction and the prevention of calculus accumulation.

NCT ID: NCT04558606 Completed - Gingivitis Clinical Trials

Efficacy of Philips Sonicare Flexcare Platinum Toothbrush® Compared to Manual Brushing in Healthy Patients: a 1 Year Follow up

SONIMAN
Start date: January 8, 2018
Phase: N/A
Study type: Interventional

Professional oral hygiene has become a customary procedure in everyday dentistry. Both manual and sonic brushes are part of normal oral hygiene education practice. Compared with manual toothbrushes, ergonomic instruments, such as sonic toothbrushes, can be a more practical and less demanding mean to remove biofilm and plaque efficiently. Studies in literature investigate the efficacy of toothbrushes in plaque removal, but the investiagator's study would validate efficacy of toothbrushes post-causal therapy, towards lower plaque accumulation, and reduction in bleeding. The objective of this study is to compare two methods (manual VS sonic) of tooth brushing in terms of impact on the gingival index and plaque index after one session of Full Mouth-Erythritol Powder Air Polishing Therapy (FM-EPAPT) in healthy patients. The hypothesis of the present randomized controlled trial is that sonic tooth brushing accumulates less plaque (-10%) than manual tooth brushing. To test this hypothesis, the patients, upon initial evaluation, will be divided in 2 study groups and, after a session of professional oral hygiene, will be instructed to use: - CONTROL: manual toothbrush - TEST: sonic toothbrush. Gingival index and plaque score will be evaluated at 2, 4, 6 weeks and 6 and 12 months.

NCT ID: NCT04484792 Completed - Clinical trials for Plaque Induced Gingivitis

Green Tea Mouthwash on Generalized Plaque- Induced Gingivitis

Start date: November 27, 2018
Phase: Phase 3
Study type: Interventional

This investigation will study the effect of green tea mouthwash as an adjunctive therapy to mechanical treatment on gingival health, and whether it has any side effects. This study also aims at increasing the awareness among health professionals and the community regarding the benefits of natural herbal products such as green tea on oral health, opposed to common chemical products. This may provide an efficient alternative for people who are sensitive to certain chemical products or who have limited sources of income and cannot afford expensive treatment of dental problems.

NCT ID: NCT04455269 Completed - Gingivitis Clinical Trials

The Efficacy of Full Mouth Erythritol Powder Air-Polishing Therapy (FM-EPAPT) Versus Traditional Ultrasonic Debridment (UD): a Randomized Controlled Study.

ERICO
Start date: May 3, 2017
Phase: N/A
Study type: Interventional

Traditional methods for plaque and calculus removal involve the use of mechanical and/or manual instruments, followed by surface polishing with rubber cups and low abrasive pastes. These instruments may cause the unintended removal of hard dental tissue, such as enamel, cementum and dentine, increasing surface roughness. Moreover, they can lead to gingival recession and consequent hypersensitivity and discomfort during treatment. New minimally-invasive approaches to biofilm removal have been recently introduced with the aim to limit the negative impact on the oral tissue. Air-polishing with low-abrasiveness powders are proven suitable for both for supra- and sub-gingival plaque removal. The use of low-abrasiveness powders could lead to several advantages, such as reduction of treatment discomfort, shorter treatment time, the possibility of cleaning areas with difficult access and minor damage on soft and hard tissues. Aim: the aim of this study is to evaluate the efficacy of the Full Mouth Erithrytol Powder Air-Polishing Therapy compared to traditional ultrasonic debridment (UD) and polishing in patient affected by gingivitis. Test hypotesis: there is no difference in clinical outcome between two methods against the hypothesis of a difference in terms of changes in Blending on Probing (BOP). To test this hypothesis, the patients, upon initial evaluation, were treated in split mouth: - The control group undergoing the standard procedure with full-mouth ultrasonic debridement and polishing with rubber cup and abrasive paste. - The study group undergoing an innovative procedure involving full-mouth air-polishing followed by ultrasonic calculus removal. Follow-ups are scheduled at 2 weeks and 1, 3, 6 and 12 months.

NCT ID: NCT04402996 Completed - Healthy Clinical Trials

Meteorin-like Levels in Individuals With Periodontitis

Start date: September 23, 2020
Phase:
Study type: Observational

Metrnl has proven to be an inflammatory-related immunoregulatory cytokine and shown to play a role in the pathogenesis of human inflammatory diseases. Metrnl is highly expressed from the oral mucosa to the esophagus. Periodontitis is a chronic inflammatory disease that can start with localized inflammatory reactions created by the supporting tissues surrounding the teeth against microorganisms and then result in loss of teeth. The authors think that Metrnl may play a role in the periodontitis. The aim of this study is to compare the Metrnl, IL-1β, and IL-10 levels of healthy and periodontitis individuals.

NCT ID: NCT04390997 Completed - Periodontitis Clinical Trials

Determination of the Levels of Lipocalin-2 and Semaphorin3A

Start date: November 15, 2019
Phase: N/A
Study type: Interventional

The aim of this clinical trial is to investigate the concentrations of Lipocalin-2 and Semaphorin 3A levels in gingival crevicular fluid in subjects with different periodontal diseases. At the same time for the periodontitis group; the purpose of this study is to analyze the correlation of these proteins with clinical parameters at the first and third months after the nonsurgical periodontal treatment.

NCT ID: NCT04317768 Completed - Dental Caries Clinical Trials

Effect of Oral Health Education on Oral Health Status, Treatment Needs and Barriers to Care

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Jordanian children have very poor oral hygiene parameters, and this is reflected as very high caries prevalence and poor gingival health conditions. This study will focus on children at social homes in the community in order to establish a baseline reference about their oral health status, treatment needs, and barriers to dental care. Also, to report the efficacy of oral health education using audio-visual aids and frequent motivation on oral health status, treatment needs and barriers to care among children at social homes in Jordan.

NCT ID: NCT04315532 Completed - Clinical trials for Pregnancy Gingivitis

The Effect of Periodontal Treatment on Stress and Pregnancy Relationship

Start date: April 2016
Phase: N/A
Study type: Interventional

There is a relationship between stress and pregnancy gingivitis. This relationship may be double-sided.

NCT ID: NCT04299347 Completed - Gingivitis Clinical Trials

Influence of the Restorative Cervical Margin Placement on the Supracrestal Tissue Attachment

Start date: November 29, 2018
Phase:
Study type: Observational

The aim of the present study is to understand the influence that marginal/subgingival restorations exert on the surrounding periodontal tissues. Even though proximal restorations are routine in everyday clinical practice, few information is available as to whether or not they may have a detrimental effect on the supracrestal tissue attachment.