Comparison of Serum Trefoil Factor 3 in Patients With Gingivitis and Periodontitis After Scaling and Root Planing — CSTF3PGPSR  

Gingivitis and Periodontal Diseases Clinical Trial

Official title: Comparison of Serum Levels of Trefoil Factor 3 in Patients With Gingivitis and Periodontitis Following Non Surgical Periodontal Therapy

Status Completed

Clinical Trial Summary

This study is intended to measure serum trefoil factor 3 at baseline and 3 months after, following nonsurgical periodontal therapy in patients with Gingivitis and Chronic Periodontitis.

Clinical Trial Description

A goal of periodontal diagnostic procedure is to provide useful information to the clinician regarding the present periodontal disease type and severity. Advances in diagnostic research are moving towards methods where periodontal risk can be identified and quantified by objective measures such as Biomarkers.

Trefoil factors (TFFs) are one such secreted molecules derived from mucin producing epithelial cells of the gastro intestinal tracts and other tissues such as Salivary glands, Parotid ducts and oral mucosa. Among three Trefoil factors reported, Trefoil Factor 3 (TFF3) is the modifying factor for signalling pathway involved in cell survival, cell proliferation and cell migration of oral keratinocytes. Hence assessing the marker levels would achieve beneficial effects on diagnosing the disease severity. ;

Related Conditions & MeSH terms

• Gingival Diseases
• Gingivitis
• Gingivitis and Periodontal Diseases
• Periodontal Diseases
• Periodontitis

• NCT number: NCT03620396
• Study type: Interventional
• Source: Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
• Status: Completed
• Phase: N/A
• Start date: October 15, 2016
• Completion date: February 19, 2017