Gingival Recession Clinical Trial
Official title:
Treatment of Local Gingival Recession With an Enamel Matrix Protein Coated Collagen Matrix - a Randomized Controlled Trial
The clinical trial studies patients with gingival recession defects (receding gums). The goal of the study is to test whether the additional use of enamel matrix derivatives (EMD), combined with the use of a coronally advance flap (CAF) and a CM (collagen matrix), shows a better outcome compared to a comparison group. The comparison group comprises patients receiving treatment with CAF and CM without the use of EMD.
The study aims to evaluate the influence of the additional use of EMD in treatment of gingival recession defects using a coronally advance flap (CAF) and a CM (collagen matrix) by means of digital and clinical assessment methods. The reference group comprises patients receiving treatment with CAF and CM without the application of EMD. In this prospective, randomized, controlled study, recession height and area, width and thickness of keratinized gingiva, pocket probing depth, and the clinical attachment level were measured at baseline and followed-up for one year. 15 patients with 24 gingival recession defects (Recession Type 1 after Cairo/Miller Class I or II) were recruited and were randomly assigned into the two treatment groups. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04462237 -
Recombinant Human Platelet-derived Growth Factor in Combination With Collagen Matrix
|
N/A | |
| Enrolling by invitation |
NCT05591326 -
The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients With Gingival Recession.
|
N/A | |
| Completed |
NCT06118177 -
Ultrasonographic Assessment of Palatal Wound Healing
|
||
| Not yet recruiting |
NCT06044870 -
Clinical Evaluation of the Modified Laterally Stretched Technique (RT2) Gingival Recession vs Tunneling With CT Grafting
|
Phase 2 | |
| Recruiting |
NCT02995070 -
Low Intensity Laser Therapy in Connective Tissue Graft for Root Coverage in Smokers
|
N/A | |
| Completed |
NCT03204565 -
Effectiveness of Adjunctive Hyaluronic Acid Application in Coronally Advanced Flap in Single Gingival Recession Sites
|
N/A | |
| Completed |
NCT01440426 -
Connective Tissue Graft Versus Mucograft Collagen Matrix for Coverage of Multiple Gingival Recession Defects
|
Phase 4 | |
| Completed |
NCT02129504 -
Two Techniques for Root Coverage With a Xenogeneic Collagen Matrix
|
N/A | |
| Completed |
NCT01547962 -
A Pilot Clinical Trial of Gintuit (TM)in Establishing a Functional Zone of Attached Gingiva
|
N/A | |
| Completed |
NCT04043039 -
Platelet Rich Fibrin in the Treatment of Full Thickness Palatal Wounds
|
N/A | |
| Recruiting |
NCT04920136 -
Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix
|
N/A | |
| Active, not recruiting |
NCT03570333 -
Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites
|
N/A | |
| Recruiting |
NCT05045586 -
MCAT With HA and sCTG Compared With sCTG Alone for Treatment of Multiple Gingival Recession: Clinical Trial
|
N/A | |
| Active, not recruiting |
NCT05101642 -
Guided Creeping Technique (GCT) in Treating Gingival Recession
|
N/A | |
| Completed |
NCT04813302 -
Influence of Anatomical Factors Upon Root Coverage
|
N/A | |
| Recruiting |
NCT06006780 -
Porcine Acellular Dermal Matrix for the Treatment of Localized Gingival Recessions A Multicenter Randomized Clinical Trial.
|
N/A | |
| Recruiting |
NCT06044727 -
MINST Versus Conventional Subgingival Instrumentation In RT1 Gingival Recession
|
N/A | |
| Enrolling by invitation |
NCT06330662 -
Effectiveness of Hyaluronic Acid on Multiple Adjacent Gingival Recessions Using a Coronally Advanced Flap
|
N/A | |
| Not yet recruiting |
NCT05472233 -
Effect of Suturing Protocols on Coronally Advanced Flap for Root Coverage Outcomes
|
N/A | |
| Recruiting |
NCT05563428 -
Free Gingival Graft Versus Connective Tissue Graft
|
N/A |