Dimensional Changes: Randomized Clinical Trial

Status Not yet recruiting

Clinical Trial Summary

The goal of this clinical trial is to evaluate the dimensional changes in the short and long-term in patients with thin gum tissues who have gum grafts placed on either denuded bone or gum grafts placed on a bone with some tissues remaining. The main question this study aims to answer is: - Does the placement of free-epithelized gingival grafts (gum grafts) on full thickness bed preparation (having all of the tissue removed from the bone) lead to similar clinical, digital, and patient-related outcomes and measurements over a period of 12 months versus split thickness bed preparation (where a small layer of tissue is left over the bone) in patients with thin gum tissue phenotypes (gum tissue is generally less than 1.5 millimeters) who are in need of soft tissue augmentation procedures? Participants will be asked to attend 8 visits, which include: (i) screening visit, (ii) prophylaxis visit, (iii) random assignment to Group A or Group B along with surgery and digital data collection, (iv) 2-week post-operative visit, (v) 6-week post-operative visit, (vi) 3-month follow-up visit, (vii) 6-month follow-up visit, (viii) 12-month follow-up visit. Also, Group A will have a free epithelialized gingival/mucosal graft (gum graft) placed on full thickness periosteal bed preparation where all of the tissue was removed (test group). Group B will have a free epithelialized gingival/mucosal graft (gum graft) on split thickness periosteal bed preparation where only a portion of the tissue was removed (control group). Researchers will compare Group A and Group B to see if there is a difference in clinical, digital, and patient-related outcomes and measurements over a period of 12 months.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Gingival Recession

Clinical Trial Details

NCT number	NCT05684068
Study type	Interventional
Source	University of Iowa
Contact	Carlos Garaicoa Pazmino, DDS, MS
Phone	(319) 467-4315
Email	carlos-garaicoapazmino@uiowa.edu
Status	Not yet recruiting
Phase	N/A
Start date	June 2024
Completion date	March 2027

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04462237` - Recombinant Human Platelet-derived Growth Factor in Combination With Collagen Matrix	N/A
Enrolling by invitation	`NCT05591326` - The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients With Gingival Recession.	N/A
Completed	`NCT06118177` - Ultrasonographic Assessment of Palatal Wound Healing
Not yet recruiting	`NCT06044870` - Clinical Evaluation of the Modified Laterally Stretched Technique (RT2) Gingival Recession vs Tunneling With CT Grafting	Phase 2
Recruiting	`NCT02995070` - Low Intensity Laser Therapy in Connective Tissue Graft for Root Coverage in Smokers	N/A
Completed	`NCT03204565` - Effectiveness of Adjunctive Hyaluronic Acid Application in Coronally Advanced Flap in Single Gingival Recession Sites	N/A
Completed	`NCT01440426` - Connective Tissue Graft Versus Mucograft Collagen Matrix for Coverage of Multiple Gingival Recession Defects	Phase 4
Completed	`NCT02129504` - Two Techniques for Root Coverage With a Xenogeneic Collagen Matrix	N/A
Completed	`NCT01547962` - A Pilot Clinical Trial of Gintuit (TM)in Establishing a Functional Zone of Attached Gingiva	N/A
Completed	`NCT04043039` - Platelet Rich Fibrin in the Treatment of Full Thickness Palatal Wounds	N/A
Recruiting	`NCT04920136` - Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix	N/A
Active, not recruiting	`NCT03570333` - Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites	N/A
Recruiting	`NCT05045586` - MCAT With HA and sCTG Compared With sCTG Alone for Treatment of Multiple Gingival Recession: Clinical Trial	N/A
Active, not recruiting	`NCT05101642` - Guided Creeping Technique (GCT) in Treating Gingival Recession	N/A
Completed	`NCT04813302` - Influence of Anatomical Factors Upon Root Coverage	N/A
Recruiting	`NCT06006780` - Porcine Acellular Dermal Matrix for the Treatment of Localized Gingival Recessions A Multicenter Randomized Clinical Trial.	N/A
Recruiting	`NCT06044727` - MINST Versus Conventional Subgingival Instrumentation In RT1 Gingival Recession	N/A
Enrolling by invitation	`NCT06330662` - Effectiveness of Hyaluronic Acid on Multiple Adjacent Gingival Recessions Using a Coronally Advanced Flap	N/A
Not yet recruiting	`NCT05472233` - Effect of Suturing Protocols on Coronally Advanced Flap for Root Coverage Outcomes	N/A
Recruiting	`NCT05563428` - Free Gingival Graft Versus Connective Tissue Graft	N/A