Clinical Trials Logo

Clinical Trial Summary

Microsurgical tunneling flap procedures using connective tissue grafts (CTG) are predictable for treating teeth with gingival recessions. Cross-linked hyaluronic acid can be used in conjunction with subepithelial palatal connective tissue grafts to improve postsurgical results. The aim of this study is to evaluate clinically the use of tunnel technique with CTG and cross-linked hyaluronic acid in addition to CTG alone for the treatment of multiple gingival recessions.


Clinical Trial Description

The treatment of multiple adjacent recession appears to be challenging for the clinician due to large surgical field, variation in teeth position in the dental arch (prominent roots), variation in recession size, thin phenotype and insufficient keratinized tissue in many teeth. Surgical treatment of all multiple recession in one dental arch during one session appears to be optimum. Surgical treatment time is longer, however patient doesn't need to undergo multiple surgeries, pharmacological therapies and postsurgical instructions. Esthetic concern seems to be one of the most common complaints from patients. Among utilized surgical techniques tunneling flap procedures using connective tissue grafts (CTG) with or without biologics such as an enamel matrix derivative (EMD) or hyaluronic acid (HA) provided the most successful outcomes for the treatment. Cross-linked hyaluronic acid can be used in conjunction with subepithelial palatal connective tissue grafts to improve postsurgical results and improving healing process. The aim of this study is to evaluate clinically the use of tunnel technique with CTG and cross-linked hyaluronic acid in addition to CTG alone for the treatment of multiple gingival recessions. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05045586
Study type Interventional
Source Medical University of Warsaw
Contact Beata Wyrebek, PhD
Phone +48692013589
Email beatawyrebek@gmail.com
Status Recruiting
Phase N/A
Start date September 15, 2021
Completion date December 1, 2022

See also
  Status Clinical Trial Phase
Completed NCT04462237 - Recombinant Human Platelet-derived Growth Factor in Combination With Collagen Matrix N/A
Enrolling by invitation NCT05591326 - The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients With Gingival Recession. N/A
Completed NCT06118177 - Ultrasonographic Assessment of Palatal Wound Healing
Not yet recruiting NCT06044870 - Clinical Evaluation of the Modified Laterally Stretched Technique (RT2) Gingival Recession vs Tunneling With CT Grafting Phase 2
Recruiting NCT02995070 - Low Intensity Laser Therapy in Connective Tissue Graft for Root Coverage in Smokers N/A
Completed NCT03204565 - Effectiveness of Adjunctive Hyaluronic Acid Application in Coronally Advanced Flap in Single Gingival Recession Sites N/A
Completed NCT01440426 - Connective Tissue Graft Versus Mucograft Collagen Matrix for Coverage of Multiple Gingival Recession Defects Phase 4
Completed NCT02129504 - Two Techniques for Root Coverage With a Xenogeneic Collagen Matrix N/A
Completed NCT01547962 - A Pilot Clinical Trial of Gintuit (TM)in Establishing a Functional Zone of Attached Gingiva N/A
Completed NCT04043039 - Platelet Rich Fibrin in the Treatment of Full Thickness Palatal Wounds N/A
Recruiting NCT04920136 - Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix N/A
Active, not recruiting NCT03570333 - Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites N/A
Active, not recruiting NCT05101642 - Guided Creeping Technique (GCT) in Treating Gingival Recession N/A
Completed NCT04813302 - Influence of Anatomical Factors Upon Root Coverage N/A
Recruiting NCT06006780 - Porcine Acellular Dermal Matrix for the Treatment of Localized Gingival Recessions A Multicenter Randomized Clinical Trial. N/A
Recruiting NCT06044727 - MINST Versus Conventional Subgingival Instrumentation In RT1 Gingival Recession N/A
Enrolling by invitation NCT06330662 - Effectiveness of Hyaluronic Acid on Multiple Adjacent Gingival Recessions Using a Coronally Advanced Flap N/A
Not yet recruiting NCT05472233 - Effect of Suturing Protocols on Coronally Advanced Flap for Root Coverage Outcomes N/A
Recruiting NCT05563428 - Free Gingival Graft Versus Connective Tissue Graft N/A
Not yet recruiting NCT03543163 - Treatment of Miller Class I and II Gingival Recession Using Non- Pedicled Buccal Fat Pad Graft as Compared to Subepithelial Connective Tissue Graft N/A