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Evaluation of Root Coverage After the Use of Coronally Advanced Flap Either With Advanced Paltelet Rich Fibrin or Subepithilial Connective Tissue Graft in Treatment of Miller Class I and II Gingival Recession.

Gingival Recession Clinical Trial

Official title:
Root Coverage After the Use of Coronally Advanced Flap With Advanced Platelet Rich Fibrin (A- PRF) Compared With Subepithelial Connective Tissue Graft in Management of Miller Class I and II Gingival Recession. A Randomized Clinical Trial

Clinical Trial Summary

patients with Miller class I , II gingival recession will be divided into 2 groups (control, intervention).the control one will receive coronally advanced flap with subepithililal connective tissue graft harvested from the palate while the intervention one will have coronally advanced flap with advanced platelet rich fibrin(A-PRF).as it represent a new generation of platelet concentrate allow for better healing and root coverage results.

Null hypothesis: In patients with Miller class I and II gingival recession, there is no difference in amount of root coverage (mm) following the application of SCTG+A-PRF compared to CAF+SCTG.

Clinical Trial Description

- Population (P): Patients with single Miller class I, II gingival recessions.

- Intervention (I): Coronally advanced flap (CAF) plus platelet rich fibrin (A-PRF).

- Comparator (C): Coronally advanced flap (CAF) plus subepithelial connective tissue graft (SCTG).

- Primary Outcome (O): Root coverage (mm).

- Time frame: 9 months.

- Study design: Randomized controlled clinical trial.

- Patients are to be selected from the outpatient clinic of the department of Oral Medicine and Periodontology-Cairo University ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03695549
Study type Interventional
Source Cairo University
Contact heba samir mahmoud, assistant lecturer
Phone 01222541606
Email heba227@gmail.com
Status Not yet recruiting
Phase N/A
Start date October 2018
Completion date October 2019
View Details
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