The Use of Cyanoacrylate on Palatal Wound

Gingival Recession Clinical Trial

Official title:

The Efficacy of Cyanoacrylate on Palatal Wound Healing and Postoperative Complaints

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03273010
• Other study ID #: Ordu Uni
• Status: Completed
• Phase: N/A
• First received: August 3, 2017
• Last updated: September 1, 2017
• Start date: December 2015
• Est. completion date: December 2016

Study information

• Verified date: September 2017
• Source: T.C. ORDU ÜNIVERSITESI
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The palatal donor site of autogenous free gingival grafts significantly influences the patient's morbidity. The purpose of this study was to evaluate the efficacy of cyanoacrylate on palatal wound healing and postoperative complaints.

Description:

A total of 35 patients were included in the study. In the test group (19 patient), cyanoacrylate was placed over the palatal wounds; conversely, the 16 control group patients were allowed to heal in a conventional way without cyanoacrylate.

Primary bleeding time, presence of secondary bleeding, postoperative pain and completion of epithelization were assessed following free gingival graft operation. As a result, compared to the control group it was determined that the cyanoacrylate tissue adhesive could reduce the postoperative morbidity and improve the wound healing.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 35
• Est. completion date: December 2016
• Est. primary completion date: December 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• no systemic diseases

• no coagulation disorders

• no drug intake in the previous 6 months that might effect the periodontal health status

• no pregnancy or lactation

• no smoking habit

• <1 mm attached gingiva width on one or two lower anterior teeth

• Miller Class I- II- III (Miller 1985) with deep gingival recession (? 3mm)

Exclusion Criteria:

• Hematologic disorders

• No cooperation

Related Conditions & MeSH terms

• Gingival Recession

Intervention

Procedure:
• Free gingival graft
Free gingival graft was harvested from palatal donor site
• Cyanoacrylate application
Periacyrl was applied on palatal wounds

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
T.C. ORDU ÜNIVERSITESI

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Primary bleeding time	The moment of active blood flow stasis that a clinical photograph could be taken by examiner without need for suction.	baseline
Secondary	Visual Analog Scale (VAS)	The changes in postoperative pain level after the operation	1-7 days after operation
Secondary	Analgesic consumption	The changes in the number of painkiller taken to relieve pain after the operation	1-7 days after operation
Secondary	Completion of epithelization	The epithelization assessed by the peroxide test	Once a week for a month after the operation