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Gingival Diseases clinical trials

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NCT ID: NCT06381700 Not yet recruiting - Oral Disease Clinical Trials

Effectiveness of MySmile App for Improving the Oral Health of Secondary School Children:

Start date: May 2024
Phase: N/A
Study type: Interventional

The goal of this cluster-randomised control trial is to assess the effectiveness of the MySmile app for improving oral health in secondary school children. The main questions it aims to answer are: 1. Will the MySmile app be more effective in improving secondary school children's dental plaque and gingival health over and above the existing school dental service (SDS)? 2. Will the MySmile app be more effective in improving secondary school children's oral health knowledge, attitudes, and behaviours over and above the existing SDS? 3. Is the MySmile app easy to use by secondary school children? 4. Is the MySmile app acceptable to use from the perspective of secondary school children? Participants in the intervention group will receive the SDS and MySmile app. The control group will receive SDS only. Therefore the researcher will compare between the intervention and control group in terms of dental plaque, gingival health, oral health knowledge, oral health attitudes and oral health behaviours.

NCT ID: NCT04167826 Not yet recruiting - Clinical trials for Gingival Disease Due to Bacteria

Oral Health Status and Diet History Analysis Among Orphan House Children From 10-14 Years in Cairo Governorate.

Start date: November 2019
Phase:
Study type: Observational

the purpose of study to determine oral health status and dietary habits among group of orphan children from 10-14 years in Cairo Governorate.

NCT ID: NCT03638973 Not yet recruiting - Biopsy Wound Clinical Trials

Comparison of Sample Biopsy Using Scalpel or Er:YAG Laser

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

For certain changes in the oral mucosa a histopathological examination of the affected tissue is indicated to confirm the diagnosis. The gold standard is the biopsy by scalpel. The aim of this study is to compare the alternative method of tissue sampling using the erbium doped yttrium aluminium garnet (Er:YAG) laser with the gold Standard.

NCT ID: NCT03588507 Not yet recruiting - Periodontitis Clinical Trials

Clinical and Radiographic Evaluation of PPF With or Without NCHA Bone in Treatment of Intrabony Defects

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

This study is meant to assess clinically and radiographically the possible predictable results regarding the use of nanocrystalline hydroxyapatite bone graft substitute together with papilla preservation flap versus papilla preservation flap alone in the treatment of periodontal intrabony defects. Patients will be randomly assigned to either test or control group. The two groups will be equally prepared for both surgical procedures. Then the decision of which group will receive (PPF techniques + Nanocrystalline hydroxyapatite bone graft) and which will receive (PPF techniques only) will be taken.

NCT ID: NCT03241277 Not yet recruiting - Clinical trials for Periodontal Diseases

Nonsurgical Periodontal Treatment in Patients With Social Phobia

NSPTSP
Start date: October 5, 2017
Phase: N/A
Study type: Interventional

Objective: To investigate the impact of nonsurgical periodontal treatment in patients with social anxiety disorder (SAD) and controls without phobia.

NCT ID: NCT02987634 Not yet recruiting - Clinical trials for Periodontal Diseases

Evaluation and Comparison of Efficacy of PeriActive Mouthwash to Chlorhexidine 0.12% Mouth Rinse

Start date: December 2018
Phase: Phase 4
Study type: Interventional

Izun Pharmaceuticals has shown that PeriActive, an oral rinse containing extracts of Sambucus nigra, Echinacea purpurea, and Centella asiatica significantly reduced gingival inflammation in an experimental gingivitis model in a phase II study, as well as in numerous other clinical trials. The product and its individual components were shown to be safe. Based on these favorable results, Izun is now seeking to demonstrate that a combined anti-bacterial/anti-inflammatory rinse will potentially enhance soft tissue healing and reduce localized inflammation following dental implant surgery equal to, or better than, a chlorhexidine rinse, with fewer side effects.

NCT ID: NCT02826109 Not yet recruiting - Pain Clinical Trials

The Efficacy of Cyanoacrylate Adhesive (PeriAcryl®90 HV) in Periodontal Wound Healing

Start date: June 2016
Phase: Phase 4
Study type: Interventional

Periodontal disease is a gum infection caused by plaque on teeth containing both bacteria and calculus (hard) deposits. These need to be removed on a regular basis to maintain gum health and to prevent teeth weakening. A routine cleaning procedure, scaling/root planing, is accompanied with post-operative soft tissue tenderness and teeth sensitivity making oral hygiene maintenance difficult during wound healing. The need for novel therapeutic approaches, such as cyanoacrylate adhesives, has been identified. It has been hypothesized that its application may provide comfort and assist patients with their daily oral self-care procedures following teeth cleaning.

NCT ID: NCT02069574 Not yet recruiting - Clinical trials for Chronic Periodontitis

Diagnosis of Periodontal Disease Using Genetic Marker in Saliva

Start date: March 2014
Phase: N/A
Study type: Interventional

The purpose of the present study is to identify the novel periodontal disease biomarkers using differentially expressed microRNA in the saliva. The severity of chronic periodontal diseases and the time of pre- and post-treatment are major classification criteria. The obtained data will secure the foundation for the development of a new non-invasive diagnostic methods for early diagnosis & prognosis prediction of periodontal disease.

NCT ID: NCT02022865 Not yet recruiting - Periodontal Disease Clinical Trials

Correlation Between Inflammatory Markers in Gingival Crevicular Fluid, Serum and Amniotic Fluids in Periodontal Pregnant Women

Start date: January 2014
Phase: N/A
Study type: Observational

The main causes of adverse pregnancy outcome(s) are reported to be maternal infection and placental, foetal, or uterine pathosis. Maternal infection and placental pathosis appear to be the most important causal factors, possibly causing pre-term labour, premature pre-term membrane rupture, or result in medically induced pregnancy interruption. There are reports of a link between poor maternal periodontal health and composite adverse pregnancy outcome of pre-term low birth weight (PLBW). however, the reason for such correlation is still not clear. In the current study the investigators will try to follow a possible path between periodontal infection and uterus physiology, by signaling out inflammatory markers that may leak from the gingival fluid into the serum and from there to the amniotic fluid. the investigators will collect GCF, serum and amniotic fluid from patients undergoing elective amniocentesis and analyse inflammatory markers in the collected samples.

NCT ID: NCT02010307 Not yet recruiting - Periodontal Disease Clinical Trials

Polymorphonuclear Cells' Sensitivity to Aggregatibacter Actinomycetemcomitans Bacteria in Patients With Aggressive Periodontitis

Start date: January 2014
Phase: N/A
Study type: Interventional

aggressive periodontitis is an inflammatory disease which damage the teeth supporting structures mostly in young patients. and has genetic basis. a specific bacteria: Aggregatibacter actinomycetemcomitans (Aa) is associated with this disease, and found to damage leukocytes by using a specific leukotoxin. in the research the investigators are aiming to find molecular and immunological basis to aggressive periodontitis.