Clinical Trials Logo

Clinical Trial Summary

Dexmedetomidine is an α2-adrenergic receptor agonist used for its sympatholytic effect, providing sedation, analgesia, and cardiovascular stabilization in the perioperative period. Remifentanil is a µ opioid agonist with a rapid onset and short duration of action, which is degraded by plasma esterase in tissues. Investigators aimed to compare the effects of dexmedetomidine and remifentanil infusions on sedation quality, side effects, and surgeon's satisfaction in geriatric outpatients who underwent cataract surgery.


Clinical Trial Description

Dexmedetomidine is an α2 agonist and remifentanil is a short-acting μ, opioid agonist. The aim of this study was to compare dexmedetomidine and remifentanil infusions used for conscious sedation in geriatric patients undergoing outpatient cataract surgery in terms of sedation quality, hemodynamic stability, and surgeon satisfaction. Eighty patients were divided into two groups according to the administration of dexmedetomidine (Group D) and remifentanil (Group R) infusion in this randomized, prospective, double-blinded study. In group D (n = 40), after a loading of 1 µg/kg dexmedetomidine in 10 minutes, 0.4 µg/kg/h-1 infusion was administered. In Group R (n = 40), remifentanil at a dose of 0.05 µg/kg-1 was administered for 10 minutes, and then 0.05 µg/kg/min-1 infusion was continued. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04935541
Study type Interventional
Source Selcuk University
Contact
Status Completed
Phase N/A
Start date March 2009
Completion date July 2010

See also
  Status Clinical Trial Phase
Completed NCT02558907 - Comparison of MMSE (Mini-Mental State Examination) and MoCA (Montreal Cognitive Assessment) in Cognitive Assessment in Geriatric Oncology N/A
Completed NCT05197127 - Efficacy of Samsung GEMS-H Device Training in Older Adults N/A
Not yet recruiting NCT06267833 - The Effect of Trunk and Upper Extremity Exercises Added to the Otago Exercise Program N/A
Completed NCT04577092 - Dual Task Training for Balance in Older Adults N/A
Completed NCT03188211 - E-learning to Improve Oral Anticoagulant Use in Hospitalized Older People With AF N/A
Recruiting NCT05605392 - Live Better at Home, Navarra ( VMNav ) N/A
Completed NCT04069962 - Effectiveness of CGA on QoL in Older Patients With Cancer Receiving Systemic Therapy N/A
Recruiting NCT02377908 - European Postgraduate Training in Geriatric Medicine N/A
Completed NCT04171752 - Elafibranor Pharmacokinetic Parameters in Elderly Healthy Volunteers Phase 1
Not yet recruiting NCT05567965 - Live Better at Home in Catalonia N/A
Withdrawn NCT04010136 - Identification of Elderly Patients in Need of Palliative Care by Family Physicians N/A
Completed NCT05400850 - YOGA Asanas and Myofascial Chain Activity in Elderly Individuals N/A
Completed NCT02118259 - Impact of Multidisciplinary Review of Drug Prescriptions on Patient Safety in a Residence for Dependent Elderly N/A
Completed NCT06209944 - Charlson Comorbidity Index and Outcome of Cardiopulmonary Resuscitation in Geriatric Patients in Hong Kong
Recruiting NCT06395779 - Comparison of Neuromuscular Exercises and Dance Therapy on Physical Performance and Kinesiophobia Results in Geriatrics N/A
Completed NCT06189430 - Effect of Vinyasa Yoga on Frailty and Anthropometric Measurements in Elderly Individuals N/A
Recruiting NCT06300281 - Comparison of Neuromuscular and Aquatic Exercise Programs on Fall Risk and Physical Function in Geriatrics N/A
Withdrawn NCT02398851 - TacTIC- Trans-disciplinary Chronic Disease Continuity of Care Model N/A
Recruiting NCT06460337 - Comparative Effects of Modified Otago and Frenkel's Exercises in Geriatric Population N/A
Recruiting NCT02604563 - Aging, Geriatric Syndromes and Clonal Hematopoiesis