Care Plans for Cancer Predisposition

Status Recruiting

Clinical Trial Summary

Develop and evaluate acceptability, feasibility, and preliminary efficacy of digital care plan and accompanying text message reminders for children and adolescents with a known Cancer Predisposition Syndromes (CPS).

Clinical Trial Description

As over 15% of pediatric cancers are associated with a cancer predisposition, it is increasingly becoming standard of care for children with cancer, as well as those with suspected hereditary risk, to be evaluated for germline cancer predisposition. Unfortunately, the increase in pediatric genetic testing has exceeded the pace of research supporting effective cancer surveillance in positive cases. Additionally, guidelines for cancer predisposition management are not easily accessed or understood by families; thus, there is often a disconnect between the understanding and retention of such information relayed to families. In this study, Investigators will develop and evaluate the acceptability, feasibility, and preliminary efficacy of digital care plans for Cancer Predisposition Syndromes (CPS) with accompanying text message reminders for children and adolescents with a known CPS. Digital care plans and text messages will be created for 10 common CPS. Investigators will use a quasi-experimental design with pre and post testing of the same cohort, before and after delivery of care plan and accompanying messages. To evaluate the impact of the digital care plans, Investigators will compare assessments of the same cohorts at 3 and 6 months time points. ;

Study Design

Related Conditions & MeSH terms

Disease Susceptibility
Genetic Predisposition
Genetic Predisposition to Disease

Clinical Trial Details

NCT number	NCT05736497
Study type	Interventional
Source	Children's Hospital of Philadelphia
Contact	Suzanne MacFarland, MD
Phone	(267) 425-1919
Email	macfarlands@chop.edu
Status	Recruiting
Phase	N/A
Start date	August 25, 2023
Completion date	September 2024

View Details

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